Brain tissue partial pressure of oxygen predicts the outcome of severe traumatic brain injury under mild hypothermia treatment | |
Sun, HT; Zheng, MH; Wang, YM; Diao, YF; Zhao, WY; Wei, ZJ; Sun, HT (reprint author), Univ Peoples Armed Police Force, Affiliated Hosp Logist, Sixth Dept Neurosurg, 220 Chenglin Rd, Tianjin 300162, Peoples R China. | |
刊名 | NEUROPSYCHIATRIC DISEASE AND TREATMENT |
2016 | |
卷号 | 12页码:2125-2129 |
关键词 | severe traumatic brain injury hypothermia brain tissue partial pressure of oxygen therapy |
ISSN号 | 1178-2021 |
DOI | 10.2147/NDT.S102929 |
文献子类 | Article |
英文摘要 | Objective: The aim of this study was to investigate the clinical significance and changes of brain tissue partial pressure of oxygen (PbtO2) in the course of mild hypothermia treatment (MHT) for treating severe traumatic brain injury (sTBI). Methods: There were 68 cases with sTBI undergoing MHT. PbtO2, intracranial pressure (ICP), jugular venous oxygen saturation (SjvO2), and cerebral perfusion pressure (CPP) were continuously monitored, and clinical outcomes were evaluated using the Glasgow Outcome Scale score. Results: Of 68 patients with sTBI, PbtO2, SjvO2, and CPP were obviously increased, but decreased ICP level was observed throughout the MHT. PbtO2 and ICP were negatively linearly correlated, while there was a positive linear correlation between PbtO2 and SjvO2. Monitoring CPP and SjvO2 was performed under normal circumstances, and a large proportion of patients were detected with low PbtO2. Decreased PbtO2 was also found after MHT. Conclusion: Continuous PbtO2 monitoring could be introduced to evaluate the condition of regional cerebral oxygen metabolism, thereby guiding the clinical treatment and predicting the outcome. |
学科主题 | Neurosciences & Neurology ; Psychiatry |
出版地 | ALBANY |
资助项目 | 国家自然科学基金项目 |
项目编号 | National Natural Science Foundation of China [814712751004949] |
语种 | 英语 |
WOS记录号 | WOS:000382209700004 |
资助机构 | NSFC |
内容类型 | 期刊论文 |
源URL | [http://ir.lzu.edu.cn/handle/262010/178538] |
专题 | 第一临床医学院_期刊论文 |
通讯作者 | Sun, HT (reprint author), Univ Peoples Armed Police Force, Affiliated Hosp Logist, Sixth Dept Neurosurg, 220 Chenglin Rd, Tianjin 300162, Peoples R China. |
推荐引用方式 GB/T 7714 | Sun, HT,Zheng, MH,Wang, YM,et al. Brain tissue partial pressure of oxygen predicts the outcome of severe traumatic brain injury under mild hypothermia treatment[J]. NEUROPSYCHIATRIC DISEASE AND TREATMENT,2016,12:2125-2129. |
APA | Sun, HT.,Zheng, MH.,Wang, YM.,Diao, YF.,Zhao, WY.,...&Sun, HT .(2016).Brain tissue partial pressure of oxygen predicts the outcome of severe traumatic brain injury under mild hypothermia treatment.NEUROPSYCHIATRIC DISEASE AND TREATMENT,12,2125-2129. |
MLA | Sun, HT,et al."Brain tissue partial pressure of oxygen predicts the outcome of severe traumatic brain injury under mild hypothermia treatment".NEUROPSYCHIATRIC DISEASE AND TREATMENT 12(2016):2125-2129. |
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