Total Synthesis of Atorvastatin

doi:10.6023/cjoc201501022

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	Total Synthesis of Atorvastatin
	Xu, L; Wang, SH; Li, H; Xu, L (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
刊名	CHINESE JOURNAL OF ORGANIC CHEMISTRY
	2015-07
卷号	35 期号:7 页码:1559-1564
关键词	atorvastatin calcium cholesterol lowering drug organic synthesis
ISSN号	0253-2786
DOI	10.6023/cjoc201501022
其他题名	阿托伐他汀的合成
文献子类	Article
英文摘要	Atorvastatin calcium (HMG-CoA reductase inhibitor) is the most widely used cholesterol lowering drugs. Its synthesis has attracted broad attention of synthetic chemistry community. In this study, a new strategy has been developed toward the synthesis of atorvastatin in 13 steps and 9% overall yield.
学科主题	Chemistry
出版地	BEIJING
资助项目	国家自然科学基金项目 ; 中央高校基本科研业务费专项资金
项目编号	National Natural Science Foundation of China [21202073, 21472077] ; Fundamental Research Funds for the Central Universities [lzujbky-2012-216, lzujbky-2014-k20]
语种	中文
CSCD记录号	CSCD:5492203
WOS记录号	WOS:000361079900021
资助机构	NSFC ; LZU
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179554]
专题	药学院_期刊论文
通讯作者	Xu, L (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Xu, L,Wang, SH,Li, H,et al. Total Synthesis of Atorvastatin[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2015,35(7):1559-1564.
APA	Xu, L,Wang, SH,Li, H,&Xu, L .(2015).Total Synthesis of Atorvastatin.CHINESE JOURNAL OF ORGANIC CHEMISTRY,35(7),1559-1564.
MLA	Xu, L,et al."Total Synthesis of Atorvastatin".CHINESE JOURNAL OF ORGANIC CHEMISTRY 35.7(2015):1559-1564.