Total Synthesis of Atorvastatin | |
Xu, L; Wang, SH; Li, H; Xu, L (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China. | |
刊名 | CHINESE JOURNAL OF ORGANIC CHEMISTRY
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2015-07 | |
卷号 | 35期号:7页码:1559-1564 |
关键词 | atorvastatin calcium cholesterol lowering drug organic synthesis |
ISSN号 | 0253-2786 |
DOI | 10.6023/cjoc201501022 |
其他题名 | 阿托伐他汀的合成 |
文献子类 | Article |
英文摘要 | Atorvastatin calcium (HMG-CoA reductase inhibitor) is the most widely used cholesterol lowering drugs. Its synthesis has attracted broad attention of synthetic chemistry community. In this study, a new strategy has been developed toward the synthesis of atorvastatin in 13 steps and 9% overall yield. |
学科主题 | Chemistry |
出版地 | BEIJING |
资助项目 | 国家自然科学基金项目 ; 中央高校基本科研业务费专项资金 |
项目编号 | National Natural Science Foundation of China [21202073, 21472077] ; Fundamental Research Funds for the Central Universities [lzujbky-2012-216, lzujbky-2014-k20] |
语种 | 中文 |
CSCD记录号 | CSCD:5492203 |
WOS记录号 | WOS:000361079900021 |
资助机构 | NSFC ; LZU |
内容类型 | 期刊论文 |
源URL | [http://ir.lzu.edu.cn/handle/262010/179554] ![]() |
专题 | 药学院_期刊论文 |
通讯作者 | Xu, L (reprint author), Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China. |
推荐引用方式 GB/T 7714 | Xu, L,Wang, SH,Li, H,et al. Total Synthesis of Atorvastatin[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2015,35(7):1559-1564. |
APA | Xu, L,Wang, SH,Li, H,&Xu, L .(2015).Total Synthesis of Atorvastatin.CHINESE JOURNAL OF ORGANIC CHEMISTRY,35(7),1559-1564. |
MLA | Xu, L,et al."Total Synthesis of Atorvastatin".CHINESE JOURNAL OF ORGANIC CHEMISTRY 35.7(2015):1559-1564. |
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