Laparoscopic vs. open Nissen's fundoplication for gastro-oesophageal reflux disease in children: A meta-analysis

doi:10.1016/j.ijsu.2016.08.017

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	Laparoscopic vs. open Nissen's fundoplication for gastro-oesophageal reflux disease in children: A meta-analysis
	Zhang, P; Tian, J; Jing, L; Wang, Q; Tian, JH; Lun, L; Lun, L (reprint author), Peoples Rd 139, Changsha, Hunan, Peoples R China.
刊名	INTERNATIONAL JOURNAL OF SURGERY
	2016-10
卷号	34 页码:10-16
关键词	Gastro-oesophageal reflux disease Children Open Nissen's fundoplication Laparoscopic Nissen's fundoplication
ISSN号	1743-9191
DOI	10.1016/j.ijsu.2016.08.017
文献子类	Review
英文摘要	Background and objective: Available evidence showed inconsistent results between laparoscopic Nissen's fundoplication (LNF) and open Nissen's fundoplication (ONF) for children with gastro-oesophageal reflux disease (GERD), so this study aimed to evaluate the efficacy and safety between LNF and ONF. Methods: Systematic, comprehensive literature searches were conducted to include randomized controlled trials (RCTs) that compared LNF and ONF for GERD. Two reviewers independently selected studies, abstracted data and assessed the methodological quality and evidence level. Data was analyzed by Review Manager Version 5.0. Risk ratio (RR) was used for dichotomous outcomes, and mean difference (MD) was used for continuous scales. Heterogeneity was estimated with the I-2 statistic, fixed-effect model was used if I-2 < 50%, and otherwise random-effects model was used. Results: Three RCTs (171 children) were included. There was not a statistical difference in mortality (RR 1.12, 95% CI 0.50 2.48), or postoperative complications (RR 0.87, 95% CI 0.61 1.25), readmission (RR 1.53, 95% CI 0.67 3.51), or hospital stay (MD 0.85, 95% CI -0.06 1.75) between LNF and ONF. But LNF was associated with more incidence of recurrence (RR 3.32, 95% CI 1.40 7.84), longer surgery duration (MD 76.33, 95% CI 69.37 83.28), but fewer retching (RR 0.11, 95% CI 0.02 0.58) than ONF. Conclusions: LNF might be as effective and safe as ONF in the short and long term, but both were associated with high risk of recurrence and mortality, especially for those children with neurological impairment, before the age of 18 months and female gender. This required a comprehensive evaluation of children before surgery. (C) 2016 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.
学科主题	Surgery
出版地	AMSTERDAM
语种	英语
WOS记录号	WOS:000386894600003
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/188726]
专题	基础医学院_期刊论文
通讯作者	Lun, L (reprint author), Peoples Rd 139, Changsha, Hunan, Peoples R China.
推荐引用方式 GB/T 7714	Zhang, P,Tian, J,Jing, L,et al. Laparoscopic vs. open Nissen's fundoplication for gastro-oesophageal reflux disease in children: A meta-analysis[J]. INTERNATIONAL JOURNAL OF SURGERY,2016,34:10-16.
APA	Zhang, P.,Tian, J.,Jing, L.,Wang, Q.,Tian, JH.,...&Lun, L .(2016).Laparoscopic vs. open Nissen's fundoplication for gastro-oesophageal reflux disease in children: A meta-analysis.INTERNATIONAL JOURNAL OF SURGERY,34,10-16.
MLA	Zhang, P,et al."Laparoscopic vs. open Nissen's fundoplication for gastro-oesophageal reflux disease in children: A meta-analysis".INTERNATIONAL JOURNAL OF SURGERY 34(2016):10-16.