Mg-II-Mediated Catalytic Asymmetric Dearomatization (CADA) Reaction of beta-Naphthols with Dialkyl Acetylenedicarboxylates

doi:10.1002/chem.201601399

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	Mg-II-Mediated Catalytic Asymmetric Dearomatization (CADA) Reaction of beta-Naphthols with Dialkyl Acetylenedicarboxylates
	Wang, LQ; Yang, DX; Li, D; Wang, PX; Wang, KZ; Wang, J; Jiang, XX; Wang, R; Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.; Jiang, XX (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China.
刊名	CHEMISTRY-A EUROPEAN JOURNAL
	2016-06-13
卷号	22 期号:25 页码:8483-8487
关键词	cyclization dearomatization fluorine magnesium naphthols
ISSN号	0947-6539
DOI	10.1002/chem.201601399
其他题名	MgII-Mediated Catalytic Asymmetric Dearomatization (CADA) Reaction of β-Naphthols with Dialkyl Acetylenedicarboxylates
文献子类	Article
英文摘要	A Mg-II-mediated catalytic asymmetric dearomatization (CADA) reaction of beta-naphthols has been developed. The reaction proceeds under ambient temperature and give a series of chiral trisubstituted olefins with good chemoselectivities, Z/E ratios, and excellent enantioselectivities. A fluorinated beta-naphthol was designed to generate chiral organofluorine skeletons through the current CADA reaction. Moreover, an interesting tandem cyclization reaction was observed in the following transformation process through an undiscovered intramolecular hydride transfer pathway.
学科主题	Chemistry
出版地	WEINHEIM
资助项目	国家自然科学基金项目 ; 长江学者和创新团队发展计划 ; 中央高校基本科研业务费专项资金 ; 甘肃省创新研究群体计划
项目编号	NSFC [91413107, 21432003, 91213302, 81473095, 21272102] ; Program for Chang-jiang Scholars and Innovative Research Team in University (PCSIRT) [IRT1137] ; Innovation Group of Gansu Province [1210RJIA002] ; Fundamental Research Funds for the Central Universities [lzujbky-2015-282]
语种	英语
WOS记录号	WOS:000380270100013
资助机构	NSFC ; MOE ; LZU ; GSSTD
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179123]
专题	基础医学院_期刊论文
通讯作者	Yang, DX; Wang, R (reprint author), Lanzhou Univ, Key Lab Preclin Study New Drugs Gansu Prov, Sch Basic Med Sci, Lanzhou 730000, Peoples R China.; Jiang, XX (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China.
推荐引用方式 GB/T 7714	Wang, LQ,Yang, DX,Li, D,et al. Mg-II-Mediated Catalytic Asymmetric Dearomatization (CADA) Reaction of beta-Naphthols with Dialkyl Acetylenedicarboxylates[J]. CHEMISTRY-A EUROPEAN JOURNAL,2016,22(25):8483-8487.
APA	Wang, LQ.,Yang, DX.,Li, D.,Wang, PX.,Wang, KZ.,...&Jiang, XX .(2016).Mg-II-Mediated Catalytic Asymmetric Dearomatization (CADA) Reaction of beta-Naphthols with Dialkyl Acetylenedicarboxylates.CHEMISTRY-A EUROPEAN JOURNAL,22(25),8483-8487.
MLA	Wang, LQ,et al."Mg-II-Mediated Catalytic Asymmetric Dearomatization (CADA) Reaction of beta-Naphthols with Dialkyl Acetylenedicarboxylates".CHEMISTRY-A EUROPEAN JOURNAL 22.25(2016):8483-8487.