Blood free fatty acids were not increased in high-fat diet induced obese insulin-resistant animals

doi:10.1016/j.orcp.2015.06.005

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	Blood free fatty acids were not increased in high-fat diet induced obese insulin-resistant animals
	Jiang, JF; Wu, YJ; Wang, XX; Lu, L; Wang, L; Zhang, BL; Cui, MX; Cui, MX (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Pharmacol, Lanzhou 730000, Peoples R China.
刊名	OBESITY RESEARCH & CLINICAL PRACTICE
	2016-03-04
卷号	10 期号:2 页码:207-210
关键词	Insulin resistance Free fatty acids Obesity Ciliary neurotrophic factor Sibutramine
ISSN号	1871-403X
DOI	10.1016/j.orcp.2015.06.005
文献子类	Article
英文摘要	Objective: The close connection between high blood FFA and insulin resistance (IR) in obese individuals is well-known. The purpose of this study was to identify whether the blood FFA increased in obese-IR animals. Methods: Obese-IR animal models were established using high-fat diet (HFD) or HFD and streptozocin, and treated with drugs. Results: The serum FFA of obese-IR animals was not increased, even significantly lower than that of normal animals, and were not significantly decreased when insulin sensitivity and obesity-related indices were ameliorated after treatment. Conclusion: The results suggest that blood FFA are unlikely the link between obesity and insulin resistance. (C) 2015 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved.
学科主题	Endocrinology & Metabolism ; Nutrition & Dietetics
出版地	OXFORD
资助项目	国家自然科学基金项目 ; 中央高校基本科研业务费专项资金 ; 甘肃省自然科学基金计划
项目编号	National Natural Science Foundation of China [30600770] ; Fundamental Research Funds for the Central Universities [lzujbky-2012-147] ; Natural Science Foundation of Gansu Province [3ZS051-A25-091]
语种	英语
WOS记录号	WOS:000375122900012
资助机构	NSFC ; LZU ; GSSTD
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/179102]
专题	基础医学院_期刊论文
通讯作者	Cui, MX (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Pharmacol, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Jiang, JF,Wu, YJ,Wang, XX,et al. Blood free fatty acids were not increased in high-fat diet induced obese insulin-resistant animals[J]. OBESITY RESEARCH & CLINICAL PRACTICE,2016,10(2):207-210.
APA	Jiang, JF.,Wu, YJ.,Wang, XX.,Lu, L.,Wang, L.,...&Cui, MX .(2016).Blood free fatty acids were not increased in high-fat diet induced obese insulin-resistant animals.OBESITY RESEARCH & CLINICAL PRACTICE,10(2),207-210.
MLA	Jiang, JF,et al."Blood free fatty acids were not increased in high-fat diet induced obese insulin-resistant animals".OBESITY RESEARCH & CLINICAL PRACTICE 10.2(2016):207-210.