Blood free fatty acids were not increased in high-fat diet induced obese insulin-resistant animals | |
Jiang, JF; Wu, YJ; Wang, XX; Lu, L; Wang, L; Zhang, BL; Cui, MX; Cui, MX (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Pharmacol, Lanzhou 730000, Peoples R China. | |
刊名 | OBESITY RESEARCH & CLINICAL PRACTICE
![]() |
2016-03-04 | |
卷号 | 10期号:2页码:207-210 |
关键词 | Insulin resistance Free fatty acids Obesity Ciliary neurotrophic factor Sibutramine |
ISSN号 | 1871-403X |
DOI | 10.1016/j.orcp.2015.06.005 |
文献子类 | Article |
英文摘要 | Objective: The close connection between high blood FFA and insulin resistance (IR) in obese individuals is well-known. The purpose of this study was to identify whether the blood FFA increased in obese-IR animals. Methods: Obese-IR animal models were established using high-fat diet (HFD) or HFD and streptozocin, and treated with drugs. Results: The serum FFA of obese-IR animals was not increased, even significantly lower than that of normal animals, and were not significantly decreased when insulin sensitivity and obesity-related indices were ameliorated after treatment. Conclusion: The results suggest that blood FFA are unlikely the link between obesity and insulin resistance. (C) 2015 Asian Oceanian Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved. |
学科主题 | Endocrinology & Metabolism ; Nutrition & Dietetics |
出版地 | OXFORD |
资助项目 | 国家自然科学基金项目 ; 中央高校基本科研业务费专项资金 ; 甘肃省自然科学基金计划 |
项目编号 | National Natural Science Foundation of China [30600770] ; Fundamental Research Funds for the Central Universities [lzujbky-2012-147] ; Natural Science Foundation of Gansu Province [3ZS051-A25-091] |
语种 | 英语 |
WOS记录号 | WOS:000375122900012 |
资助机构 | NSFC ; LZU ; GSSTD |
内容类型 | 期刊论文 |
源URL | [http://ir.lzu.edu.cn/handle/262010/179102] ![]() |
专题 | 基础医学院_期刊论文 |
通讯作者 | Cui, MX (reprint author), Lanzhou Univ, Sch Basic Med Sci, Inst Pharmacol, Lanzhou 730000, Peoples R China. |
推荐引用方式 GB/T 7714 | Jiang, JF,Wu, YJ,Wang, XX,et al. Blood free fatty acids were not increased in high-fat diet induced obese insulin-resistant animals[J]. OBESITY RESEARCH & CLINICAL PRACTICE,2016,10(2):207-210. |
APA | Jiang, JF.,Wu, YJ.,Wang, XX.,Lu, L.,Wang, L.,...&Cui, MX .(2016).Blood free fatty acids were not increased in high-fat diet induced obese insulin-resistant animals.OBESITY RESEARCH & CLINICAL PRACTICE,10(2),207-210. |
MLA | Jiang, JF,et al."Blood free fatty acids were not increased in high-fat diet induced obese insulin-resistant animals".OBESITY RESEARCH & CLINICAL PRACTICE 10.2(2016):207-210. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论