Probiotics in patients with severe acute pancreatitis: a meta-analysis

doi:10.1007/s00423-008-0379-2

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	Probiotics in patients with severe acute pancreatitis: a meta-analysis
	Sun, SL; Yang, KH; He, XD; Tian, JH; Ma, B; Jiang, L; Yang, KH (reprint author), Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, Lanzhou 730000, Peoples R China.
刊名	LANGENBECKS ARCHIVES OF SURGERY
	2009-01
卷号	394 期号:1 页码:171-177
关键词	Probiotics Severe acute pancreatitis Meta-analysis
ISSN号	1435-2443
DOI	10.1007/s00423-008-0379-2
文献子类	Article
英文摘要	Background This study focuses on probiotics in patients with severe acute pancreatitis. It assesses whether enteral feeding with probiotics use reduces infected necrosis and death in severe acute pancreatitis. Materials and methods We searched the Cochrane Library, Medline, Embase, and Chinese Biomedicine Database. Quality assessment and data extraction were done by two reviewers independently. The statistical analysis was performed by RevMan4.2.10 software. The result was expressed with odds ratio ( OR) for the categorical variable. Results Four studies were included. The result showed that using probiotics could not reduce the risk of infection pancreatic necrosis (OR = 0.56, 95% CI [0.13, 2.35]). There is no significant difference between the two groups in mortality (OR = 0.83, 95% CI [0.14, 4.83]), the mean duration of hospital (WMD = -1.20, 95% CI [-13.13, 10.92]) and the required operation (OR = 0.59, 95% CI [0.11, 3.07]). Conclusion The present study showed the enteral feeding with probiotic could not reduce the infected necrosis and mortality. Future large-scale, high-quality, placebo-controlled, double-blind trials are needed.
学科主题	Surgery
出版地	NEW YORK
语种	英语
WOS记录号	WOS:000260768100019
内容类型	期刊论文
源URL	[http://ir.lzu.edu.cn/handle/262010/121398]
专题	基础医学院_期刊论文
通讯作者	Yang, KH (reprint author), Lanzhou Univ, Sch Basic Med Sci, Evidence Based Med Ctr, Lanzhou 730000, Peoples R China.
推荐引用方式 GB/T 7714	Sun, SL,Yang, KH,He, XD,et al. Probiotics in patients with severe acute pancreatitis: a meta-analysis[J]. LANGENBECKS ARCHIVES OF SURGERY,2009,394(1):171-177.
APA	Sun, SL.,Yang, KH.,He, XD.,Tian, JH.,Ma, B.,...&Yang, KH .(2009).Probiotics in patients with severe acute pancreatitis: a meta-analysis.LANGENBECKS ARCHIVES OF SURGERY,394(1),171-177.
MLA	Sun, SL,et al."Probiotics in patients with severe acute pancreatitis: a meta-analysis".LANGENBECKS ARCHIVES OF SURGERY 394.1(2009):171-177.