Synthesis, Crystal Structure and Biological Activity of N-tert-butyl-N-(4-methyl-1,2,3-thiadiazole)-5-yl-N &#039;-(4-methyl-1,2,3-thiadiazole)-5-formyl-N -3,5-dichloropyridin-2-yl-diacylhydrazine

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	Synthesis, Crystal Structure and Biological Activity of N-tert-butyl-N-(4-methyl-1,2,3-thiadiazole)-5-yl-N '-(4-methyl-1,2,3-thiadiazole)-5-formyl-N -3,5-dichloropyridin-2-yl-diacylhydrazine
	Wang Huan 1; Fu Yifeng 1; Fan Zhijin 1; Song Haibin 1; Wu Qingjun 2; Zhang Youjun 2; Belskaya N. P 3; Bakulev V. A 3
刊名	Chinese Journal of Structural Chemistry
	2011
卷号	30 期号:3 页码:412-416
关键词	crystal structure 1,2,3-thiadiazole synthesis biological activity
ISSN号	0254-5861
英文摘要	The title compound N-tert-butyl-N-(4-methyl- 1,2,3-thiadiazole)-5-yl-N'-(4-me-thyl-1,2,3-thiadiazole)-5-formyl-N'-3,5-dichloropyrid-2-yl-diacylhydrazines (C_(18)H_(17)C_(12)N_7O_3S_2, Mr = 514.41) has been synthesized by the reaction of N-tert-butyl-N'-3,6-dichloropyridine-2-formyl hydrazine with 4-methyl-1,2,3- thiadiazole-5-carbonyl chloride and triethylamine, and its structure was characterized by ~1H NMR, HR MS, and single-crystal X-ray diffraction. The crystal of the title compound belongs to monoclinic, space group C2/c with a = 27.726(8), b = 11.045(3), c = 14.507(4) A, β = 96.758(4)°, Z = 8, V= 4412(2) A~3, D_c = 1.549 g/cm~3, μ = 0.521 mm~(-1), F(000) = 2112, R = 0.0405 and wR = 0.1153. X-ray analysis indicates that all rings are non-planar in this molecule. The bioassay results indicate that both the title compound and the positive control RH-5992 have weak fungicide activities, while the title compound has good insecticidal activity against Plutella xylostella L. and no insecticidal activity against Culex pipiens pallens
学科主题	化学
语种	英语
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/100639]
专题	蔬菜花卉研究所
作者单位	1.Nankai University, State Key Laboratory of Elemento Organic Chemistry, Tianjin, 300071 2.Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, 100094 3.The Ural Federal University Named after the First President of Russia B. N. Yeltsin, Yeltsin UrFU, Russia, Ekaterinburg, 620002
推荐引用方式 GB/T 7714	Wang Huan,Fu Yifeng,Fan Zhijin,et al. Synthesis, Crystal Structure and Biological Activity of N-tert-butyl-N-(4-methyl-1,2,3-thiadiazole)-5-yl-N '-(4-methyl-1,2,3-thiadiazole)-5-formyl-N -3,5-dichloropyridin-2-yl-diacylhydrazine[J]. Chinese Journal of Structural Chemistry,2011,30(3):412-416.
APA	Wang Huan.,Fu Yifeng.,Fan Zhijin.,Song Haibin.,Wu Qingjun.,...&Bakulev V. A.(2011).Synthesis, Crystal Structure and Biological Activity of N-tert-butyl-N-(4-methyl-1,2,3-thiadiazole)-5-yl-N '-(4-methyl-1,2,3-thiadiazole)-5-formyl-N -3,5-dichloropyridin-2-yl-diacylhydrazine.Chinese Journal of Structural Chemistry,30(3),412-416.
MLA	Wang Huan,et al."Synthesis, Crystal Structure and Biological Activity of N-tert-butyl-N-(4-methyl-1,2,3-thiadiazole)-5-yl-N '-(4-methyl-1,2,3-thiadiazole)-5-formyl-N -3,5-dichloropyridin-2-yl-diacylhydrazine".Chinese Journal of Structural Chemistry 30.3(2011):412-416.