Synthesis and characterization of electroactive and biodegradable ABA block copolymer of polylactide and aniline pentamer

	Synthesis and characterization of electroactive and biodegradable ABA block copolymer of polylactide and aniline pentamer
	Huang LH ; Hu J ; Lang L ; Wang X ; Zhang PB ; Jing XB ; Wang XH ; Chen XS ; Lelkes PI ; MacDiarmid AG ; Wei Y
刊名	biomaterials
	2007
卷号	28 期号:10 页码:1741-1751
关键词	ELECTRICALLY CONDUCTING POLYMER POLYANILINE BIOCOMPATIBILITY STIMULATION SEPARATIONS NANOFIBERS CORROSION STEELS FILMS GAS
ISSN号	0142-9612
通讯作者	chen xs
中文摘要	a triblock copolymer pla-b-ap-b-pla (pap) of polylactide (pla) and aniline pentamer (ap) with the unique properties of being both electroactive and biodegradable is synthesized by coupling an electroactive carboxyl-capped ap with two biodegradable bihydroxyl-capped plas via a condensation reaction. three different molecule weight pap copolymers are prepared. the pap copolymers exhibit excellent electroactivity similar to the ap and polyaniline, which may stimulate cell proliferation and differentiation. the electrical conductivity of the pap2 copolymer film (similar to 5 x 10(-6) s/cm) is in the semiconducting region. transmission electron microscopic results suggest that there is microphase separation of the two block segments in the copolymer, which might contribute to the observed conductivity. the biodegradation and biocompatibility experiments in vitro prove the copolymer is biodegradable and biocompatible. moreover, these new block copolymer shows good solubility in common organic solvents, leading to the system with excellent processibility. these biodegradable pap copolymers with electroactive function thus possess the properties that would be potentially used as scaffold materials for neuronal or cardiovascular tissue engineering.
收录类别	SCI
语种	英语
WOS记录号	WOS:000244436000001
公开日期	2010-07-13
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/14437]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Huang LH,Hu J,Lang L,et al. Synthesis and characterization of electroactive and biodegradable ABA block copolymer of polylactide and aniline pentamer[J]. biomaterials,2007,28(10):1741-1751.
APA	Huang LH.,Hu J.,Lang L.,Wang X.,Zhang PB.,...&Wei Y.(2007).Synthesis and characterization of electroactive and biodegradable ABA block copolymer of polylactide and aniline pentamer.biomaterials,28(10),1741-1751.
MLA	Huang LH,et al."Synthesis and characterization of electroactive and biodegradable ABA block copolymer of polylactide and aniline pentamer".biomaterials 28.10(2007):1741-1751.