Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis

doi:10.1038/ncb2219

CORC > 中国农业科学院 > 作物科学研究所

	Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis
	Li, Gang 1; Siddiqui, Hamad 2; Teng, Yibo 3; Lin, Rongcheng 4; Wan, Xiang-yuan 5; Li, Jigang 1; Lau, On-Sun 1; Ouyang, Xinhao 1; Dai, Mingqiu 1; Wan, Jianmin 6
刊名	NATURE CELL BIOLOGY
	2011
卷号	13 期号:5 页码:616-U275
ISSN号	1465-7392
DOI	10.1038/ncb2219
通讯作者	Li, Gang
英文摘要	The circadian clock controls many metabolic, developmental and physiological processes in a time-of-day-specific manner in both plants and animals(1,2). The photoreceptors involved in the perception of light and entrainment of the circadian clock have been well characterized in plants(3). However, how light signals are transduced from the photoreceptors to the central circadian oscillator, and how the rhythmic expression pattern of a clock gene is generated and maintained by diurnal light signals remain unclear. Here, we show that in Arabidopsis thaliana, FHY3, FAR1 and HY5, three positive regulators of the phytochrome A signalling pathway, directly bind to the promoter of ELF4, a proposed component of the central oscillator, and activate its expression during the day, whereas the circadian-controlled CCA1 and LHY proteins directly suppress ELF4 expression periodically at dawn through physical interactions with these transcription-promoting factors. Our findings provide evidence that a set of light- and circadian-regulated transcription factors act directly and coordinately at the ELF4 promoter to regulate its cyclic expression, and establish a potential molecular link connecting the environmental light dark cycle to the central oscillator.
学科主题	Cell Biology ; CELL BIOLOGY
语种	英语
出版者	NATURE PUBLISHING GROUP
WOS记录号	WOS:000290148700021
内容类型	期刊论文
源URL	[http://111.203.20.206/handle/2HMLN22E/5318]
专题	作物科学研究所
作者单位	1.Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA 2.Royal Holloway Univ London, Sch Biol Sci, Egham TW20 0EX, Surrey, England 3.Hangzhou Normal Univ, Coll Life & Environm Sci, Hangzhou 310036, Zhejiang, Peoples R China 4.Chinese Acad Sci, Key Lab Photobiol, Inst Bot, Beijing 100093, Peoples R China 5.Natl Engn Res Ctr Crop Mol Design, Beijing 100085, Peoples R China 6.Chinese Acad Agr Sci, Inst Crop Sci, Beijing 100081, Peoples R China 7.Hunan Hybrid Rice Res Ctr, Changsha 410125, Hunan, Peoples R China
推荐引用方式 GB/T 7714	Li, Gang,Siddiqui, Hamad,Teng, Yibo,et al. Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis[J]. NATURE CELL BIOLOGY,2011,13(5):616-U275.
APA	Li, Gang.,Siddiqui, Hamad.,Teng, Yibo.,Lin, Rongcheng.,Wan, Xiang-yuan.,...&Wang, Haiyang.(2011).Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis.NATURE CELL BIOLOGY,13(5),616-U275.
MLA	Li, Gang,et al."Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis".NATURE CELL BIOLOGY 13.5(2011):616-U275.