Three new elemanolides from the seeds of Vernonia anthelmintica.

CORC > 新疆理化技术研究所 > 中国科学院新疆理化技术研究所 > 省部共建新疆特有药用资源利用重点实验室

	Three new elemanolides from the seeds of Vernonia anthelmintica.
	Turak, Ablajan; Aisa, Haji Akber
刊名	Journal of Asian natural products research
	2017
期号	7 页码:1-8
关键词	Compositae Vernonia anthelmintica cytotoxicity elemanolide sesquiterpenoid
英文摘要	Three new elemanolides, named vernonilides D (1), E (2), and F (3), along with four known sesquiterpenoids, including two elemanolides (4, 5), a guaianolide (6), and a germacranolide (7) were isolated from the seeds of Vernonia anthelmintica. The structures of them were elucidated based on 1D and 2D NMR experiments and comparison with published data. Cytotoxicity of the compounds against four human tumor cell lines was assayed. 6 showed strongly inhibitory effect against HCT-15 and PC-3 cell lines with IC50 values of 0.56 and 0.69muM, respectively. The new compounds showed moderate cytotoxicity against four cell lines with IC50 values ranging from 9.1 to 28.1muM.
收录类别	SCI
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/4842]
专题	新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室
作者单位	a State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization , Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Urumqi 830011 , China.
推荐引用方式 GB/T 7714	Turak, Ablajan,Aisa, Haji Akber. Three new elemanolides from the seeds of Vernonia anthelmintica.[J]. Journal of Asian natural products research,2017(7):1-8.
APA	Turak, Ablajan,&Aisa, Haji Akber.(2017).Three new elemanolides from the seeds of Vernonia anthelmintica..Journal of Asian natural products research(7),1-8.
MLA	Turak, Ablajan,et al."Three new elemanolides from the seeds of Vernonia anthelmintica.".Journal of Asian natural products research .7(2017):1-8.