Electrospinning of multicomponent ultrathin fibrous nonwovens for semi-occlusive wound dressings

	Electrospinning of multicomponent ultrathin fibrous nonwovens for semi-occlusive wound dressings
	Hong YL ; Li YA ; Zhuang XL ; Chen XS ; Jing XB
刊名	journal of biomedical materials research part a
	2009
卷号	89a 期号:2 页码:345-354
关键词	TISSUE ENGINEERING SCAFFOLDS SILVER NANOPARTICLES POLY(VINYL ALCOHOL) FIBERS NANOFIBERS POLYMER MEMBRANE HYDROGEL BEHAVIOR IODINE
ISSN号	1549-3296
通讯作者	chen xs
中文摘要	this work describes the design and assembly of multifunctional and cost-efficient composite fiber nonwovens as semi-occlusive wound dressings using a simple electrospinning process to incorporate a variety of functional components into an ultrathin fiber. these components include non-hydrophilic poly(l-lactide) (plla) as fibrous backbone, hydrophilic poly(vinyl pyrrolidone)iodine (pvp-i), tio2 nanoparticles, zinc chloride as antimicrobial, odor-controlling, and antiphlogistic agents, respectively. the process of synthesis starts with a multicomponent solution of plla, pvp, tio2 nanoparticles plus zinc chloride, in which tio2 nanoparticles are synthesized by in situ hydrolysis of tio2 precursors in a pvp solution for the sake of obtaining the particle-uniformly dispersive solution. subsequent electrospinning generates the corresponding composite fibers. a further iodine vapor treatment to the composite fibers combines iodine with pvp to produce the pvp-i complexes. experiments indicate that the assembled composite fibers (300-400 nm) possess the ointment-releasing characteristic and the phase-separate, core-sheath structures in which pvp-i residing in fiber surface layer becomes the sheath, and plla distributing inside the fiber acts as the core.
收录类别	SCI
语种	英语
WOS记录号	WOS:000264850200007
公开日期	2010-06-18
内容类型	期刊论文
源URL	[http://202.98.16.49/handle/322003/12941]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Hong YL,Li YA,Zhuang XL,et al. Electrospinning of multicomponent ultrathin fibrous nonwovens for semi-occlusive wound dressings[J]. journal of biomedical materials research part a,2009,89a(2):345-354.
APA	Hong YL,Li YA,Zhuang XL,Chen XS,&Jing XB.(2009).Electrospinning of multicomponent ultrathin fibrous nonwovens for semi-occlusive wound dressings.journal of biomedical materials research part a,89a(2),345-354.
MLA	Hong YL,et al."Electrospinning of multicomponent ultrathin fibrous nonwovens for semi-occlusive wound dressings".journal of biomedical materials research part a 89a.2(2009):345-354.