Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors

	Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors
	Li BL ; Qin CJ ; Li T ; Wang LX ; Dong SJ
刊名	analytical chemistry
	2009
卷号	81 期号:9 页码:3544–3550
关键词	PEPTIDE NUCLEIC-ACID SINGLE-STRANDED-DNA COLORIMETRIC DETECTION CHEMICAL SENSORS APTAMER FLUORESCENCE WATER RECOGNITION COMPLEXES SELECTION
ISSN号	0003-2700
通讯作者	wang lx
中文摘要	here, a fluorescent switch is constructed combining hemin, hemin aptamer, and a newly synthesized anionic conjugated polymer (acp), poly(9,9-bis(6'-phosphate-hexyl) fluorenealt-1,4-phenylene) sodium salt (pfhpna/pfp). in the "off-state", the fluorescence of pfp is sensitively quenched by hemin, with a high k-sv value of similar to 10(7). while in the "on-state", the formation of the aptamer/hemin complex recovers the fluorescence intensity. the fluorescent switch is sensitive and selective to hemin. to testify the universality and practicality of the fluorescent switch, a series of label-free dna-related sensing platforms are developed, containing three dna sensing strategies and one atp recognition strategy. the fluorescent switch developed is simple, sensitive, and universal, which extends applications of the anionic conjugated polymers.
收录类别	SCI
语种	英语
WOS记录号	WOS:000265632400047
公开日期	2010-05-27
内容类型	期刊论文
源URL	[http://202.98.16.49/handle/322003/11887]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Li BL,Qin CJ,Li T,et al. Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors[J]. analytical chemistry,2009,81(9):3544–3550.
APA	Li BL,Qin CJ,Li T,Wang LX,&Dong SJ.(2009).Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors.analytical chemistry,81(9),3544–3550.
MLA	Li BL,et al."Flourescent Switch Constructed Based on Hemin-Sensitive Anionic Conjugated Polymer and Its Applications in DNA-Related Sensors".analytical chemistry 81.9(2009):3544–3550.