Controlling Capillary-Driven Fluid Transport in Paper-Based Microfluidic Devices Using a Movable Valve

CORC > 烟台海岸带研究所 > 中国科学院烟台海岸带研究所 > 中科院海岸带环境过程与生态修复重点实验室

	Controlling Capillary-Driven Fluid Transport in Paper-Based Microfluidic Devices Using a Movable Valve
	Li, Bowei1 ; Yu, Lijuan 2; Qi, Ji 3; Fu, Longwen 1; Zhang, Peiqing 2; Chen, Lingxin1,2
刊名	ANALYTICAL CHEMISTRY
	2017-06-06
卷号	89 期号:11 页码:5708-5713
ISSN号	0003-2700
英文摘要	This paper describes a novel, strategy for fabricating the movable valve on paper-based microfluidic devices to manipulate capillary-driven fluids. The movable valve fabrication is first realized using hollow rivets as the-holding center it, control the paper channel in different layer movement that Jesuits in the :channel's connection or disconnection. The relatively simple Valve fabrication procedure is robust, Versatile, and, compatible with microfluidic paper-based analytical devices (mu PADs) with differing levels of complexity. It is remarkable that the movable valve can be convenient and free to control fluid without the timing setting; advantages that make it user-friendly for untrained users to carry out the complex multistep operations. For the, performance of the Movable valve to be-verified, several different designs of mu PADs were tested and obtained with satisfactory results. In addition; in the proof-of-concept enzyme-linked immunosorbent assay experiments, we demonstrate the use of these valves in mu PADs for the successful analysis of samples of carcino-embryonic antigen, showing good sensitivity and reproducibility. We hope this technique will open new avenues for the fabrication of paper-based valves in an easily adoptable and widely available way on mu PADs and provide potential point-of-Care applications in the future.
研究领域[WOS]	Chemistry
关键词[WOS]	CHEMILUMINESCENCE IMMUNOASSAY ; LAYERED PAPER ; LOW-COST ; FLOW ; IMMUNODEVICE ; ARRAYS
收录类别	SCI
语种	英语
WOS记录号	WOS:000403036800012
内容类型	期刊论文
源URL	[http://ir.yic.ac.cn/handle/133337/22530]
专题	烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室烟台海岸带研究所_山东省海岸带环境工程技术研究中心
作者单位	1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 2.Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China 3.Yantai Univ, Sch Environm & Mat Engn, Yantai 264005, Peoples R China
推荐引用方式 GB/T 7714	Li, Bowei,Yu, Lijuan,Qi, Ji,et al. Controlling Capillary-Driven Fluid Transport in Paper-Based Microfluidic Devices Using a Movable Valve[J]. ANALYTICAL CHEMISTRY,2017,89(11):5708-5713.
APA	Li, Bowei,Yu, Lijuan,Qi, Ji,Fu, Longwen,Zhang, Peiqing,&Chen, Lingxin.(2017).Controlling Capillary-Driven Fluid Transport in Paper-Based Microfluidic Devices Using a Movable Valve.ANALYTICAL CHEMISTRY,89(11),5708-5713.
MLA	Li, Bowei,et al."Controlling Capillary-Driven Fluid Transport in Paper-Based Microfluidic Devices Using a Movable Valve".ANALYTICAL CHEMISTRY 89.11(2017):5708-5713.