Highly Enantioselective Synthesis of alpha-Trifluoromethyldihydropyrans Using a Chiral Trifluoroethyl-substituted Thiourea Catalyst Derived from Amino Acid

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	Highly Enantioselective Synthesis of alpha-Trifluoromethyldihydropyrans Using a Chiral Trifluoroethyl-substituted Thiourea Catalyst Derived from Amino Acid
	Li P(李鹏) ; Zhao G(赵刚) ; Zhu SZ(朱仕正)
刊名	Chin. J. Chem.
	2011
卷号	29 期号:12 页码:2749-2758
ISSN号	1001-604X
其他题名	氨基酸衍生的三氟乙基取代的硫脲类催化剂催化的高对映选择性合成α-三氟甲基二氢吡喃结构
通讯作者	赵刚 ; 朱仕正
英文摘要	An enantioselective Michael addition of ethyl 4,4,4-trifluoro-3-oxobutanoate to a,alpha,beta-unsaturated ketone esters using a chiral alkyl-substituted thiourea catalyst is reported. Excellent levels of stereo-induction (up to 98% cc) under mild reaction conditions were obtained to afford the corresponding alpha-trifluoromethyldihydropyrans.
学科主题	有机氟化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/cjoc.201100034
语种	英语
WOS记录号	WOS:000298016700032
公开日期	2013-01-18
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/14536]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	Li P,Zhao G,Zhu SZ. Highly Enantioselective Synthesis of alpha-Trifluoromethyldihydropyrans Using a Chiral Trifluoroethyl-substituted Thiourea Catalyst Derived from Amino Acid[J]. Chin. J. Chem.,2011,29(12):2749-2758.
APA	李鹏,赵刚,&朱仕正.(2011).Highly Enantioselective Synthesis of alpha-Trifluoromethyldihydropyrans Using a Chiral Trifluoroethyl-substituted Thiourea Catalyst Derived from Amino Acid.Chin. J. Chem.,29(12),2749-2758.
MLA	李鹏,et al."Highly Enantioselective Synthesis of alpha-Trifluoromethyldihydropyrans Using a Chiral Trifluoroethyl-substituted Thiourea Catalyst Derived from Amino Acid".Chin. J. Chem. 29.12(2011):2749-2758.