One-pot three-component reaction of fluoroalkanesulfonyl azide, vinyl ether and aldehyde: the formation of polysubstituted fluorinated oxazolidines diastereoselective; oxazolidine

CORC > 上海有机化学研究所 > 中国科学院上海有机化学研究所 > 中科院有机氟化学重点实验室

	One-pot three-component reaction of fluoroalkanesulfonyl azide, vinyl ether and aldehyde: the formation of polysubstituted fluorinated oxazolidines diastereoselective; oxazolidine
	He P(何萍) ; Zhu SZ(朱仕正)
刊名	Tetrahedron
	2005
卷号	61 期号:25 页码:6088-6096
ISSN号	0040-4020
其他题名	氟烷基磺酰叠氮, 烯基醚和醛的三组分一锅反应生成多取代含氟噁唑烷
通讯作者	朱仕正
英文摘要	Efficient and diastereoselective synthesis of highly substituted fluorinated oxazolidines was achieved via a one-pot three-component reaction of fluoroalkanesulfonyl azides 1, vinyl ether 2 and various aldehydes at 0 degrees C within 10 min in moderate to good diastereoselectivities (synlanti). A competing process could be involved in the initial step and an unstable fluorinated aziridine was postulated as the intermediate for these reactions. Additionally, rational transition states were also proposed to elucidate the diastereoselectivities. This synthetic method provides a convenient and expeditious access to N-per(poly)fluoroalkanesulfonyl oxazolidines. (c) 2005 Elsevier Ltd. All rights reserved.
学科主题	有机氟化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1016/j.tet.2005.04.020
语种	英语
公开日期	2013-01-18
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/14350]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	He P,Zhu SZ. One-pot three-component reaction of fluoroalkanesulfonyl azide, vinyl ether and aldehyde: the formation of polysubstituted fluorinated oxazolidines diastereoselective; oxazolidine[J]. Tetrahedron,2005,61(25):6088-6096.
APA	何萍,&朱仕正.(2005).One-pot three-component reaction of fluoroalkanesulfonyl azide, vinyl ether and aldehyde: the formation of polysubstituted fluorinated oxazolidines diastereoselective; oxazolidine.Tetrahedron,61(25),6088-6096.
MLA	何萍,et al."One-pot three-component reaction of fluoroalkanesulfonyl azide, vinyl ether and aldehyde: the formation of polysubstituted fluorinated oxazolidines diastereoselective; oxazolidine".Tetrahedron 61.25(2005):6088-6096.