1,3-dipolar cycloaddition of difluoro(methylene)cyclopropanes with nitrones: Efficient synthesis of 3,3-difluorinated tetrahydropyridinols

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	1,3-dipolar cycloaddition of difluoro(methylene)cyclopropanes with nitrones: Efficient synthesis of 3,3-difluorinated tetrahydropyridinols
	Hang XC(杭晓春) ; Chen QY(陈庆云) ; Xiao JC(肖吉昌)
刊名	Synlett
	2008
期号	13 页码:1989-1992
ISSN号	0936-5214
其他题名	二氟(亚甲基)环丙烷与硝酮的1,3-偶极环加成反应：3,3-二氟-四氢吡啶醇的高效合成
通讯作者	肖吉昌
英文摘要	Difluoro-substituted spirocyclopropaneisoxazolidines were formed by 1.3-dipolar cycloaddition of difluoro(methylene)cyclopropanes (F(2)MCPs) with nitrones in high yields. The [3+2]-cycloaddition reactions exhibited good regioselectivity and high stereoselectivity. The cycloadducts could rearrange further to form highly substituted 3,3-difluorinated tetrahydropyridinols.
学科主题	有机氟化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1055/s-2008-1077966
语种	英语
WOS记录号	WOS:000258374600014
公开日期	2013-01-17
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/13662]
专题	上海有机化学研究所_中科院有机氟化学重点实验室
推荐引用方式 GB/T 7714	Hang XC,Chen QY,Xiao JC. 1,3-dipolar cycloaddition of difluoro(methylene)cyclopropanes with nitrones: Efficient synthesis of 3,3-difluorinated tetrahydropyridinols[J]. Synlett,2008(13):1989-1992.
APA	杭晓春,陈庆云,&肖吉昌.(2008).1,3-dipolar cycloaddition of difluoro(methylene)cyclopropanes with nitrones: Efficient synthesis of 3,3-difluorinated tetrahydropyridinols.Synlett(13),1989-1992.
MLA	杭晓春,et al."1,3-dipolar cycloaddition of difluoro(methylene)cyclopropanes with nitrones: Efficient synthesis of 3,3-difluorinated tetrahydropyridinols".Synlett .13(2008):1989-1992.