Easily accessible C-2-symmetric chiral bicyclo[3.3.0] dienes as ligands for rhodium-catalyzed asymmetric 1,4-addition

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	Easily accessible C-2-symmetric chiral bicyclo[3.3.0] dienes as ligands for rhodium-catalyzed asymmetric 1,4-addition
	Feng CG(冯陈国) ; Wang ZQ(王智谦) ; Tian P(田平) ; Xu MH(徐明华) ; Lin GQ(林国强)
刊名	Chem.-Asian J.
	2008
卷号	3 期号:8-9 页码:1511-1516
ISSN号	1861-4728
其他题名	Easily accessible C-2-symmetric chiral bicyclo[3.3.0] dienes as ligands for rhodium-catalyzed asymmetric 1,4-addition
通讯作者	徐明华 ; 林国强
英文摘要	The synthesis of a new type of C-2-symmetric chiral diene ligands with a nonbridged bicyclic [3.3.0] backbone was successfully introduced. Using highly efficient lipase-catalyzed transesterification and Suzuki-coupling strategies, a broad family of enantiopure 3,6-disubstituted bicyclo[3.3.0] dienes with different electronic and steric properties could be easily prepared. The application of these new diene ligands in the Rh-catalyzed asymmetric 1,4-addition of arylboronic acids to alpha,beta-unsaturated carbonyl compounds have been examined, and excellent enantioselectivities (up to 98% ee) as well as good yields are achieved under very mild reaction conditions at room temperature.
学科主题	金属有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1002/asia.200800049
语种	英语
WOS记录号	WOS:000259119400036
公开日期	2013-02-20
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/16669]
专题	上海有机化学研究所_中科院天然产物有机化学重点实验室
推荐引用方式 GB/T 7714	Feng CG,Wang ZQ,Tian P,et al. Easily accessible C-2-symmetric chiral bicyclo[3.3.0] dienes as ligands for rhodium-catalyzed asymmetric 1,4-addition[J]. Chem.-Asian J.,2008,3(8-9):1511-1516.
APA	冯陈国,王智谦,田平,徐明华,&林国强.(2008).Easily accessible C-2-symmetric chiral bicyclo[3.3.0] dienes as ligands for rhodium-catalyzed asymmetric 1,4-addition.Chem.-Asian J.,3(8-9),1511-1516.
MLA	冯陈国,et al."Easily accessible C-2-symmetric chiral bicyclo[3.3.0] dienes as ligands for rhodium-catalyzed asymmetric 1,4-addition".Chem.-Asian J. 3.8-9(2008):1511-1516.