First examples of Friedel-Crafts alkylation using ketals as alkylating agents: an expeditious access to the benzene-fused8-oxabicyclo[3.2.1]octanering system.

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	First examples of Friedel-Crafts alkylation using ketals as alkylating agents: an expeditious access to the benzene-fused8-oxabicyclo[3.2.1]octanering system.
	Fan JF(范俊发) ; Wu YK(伍贻康) ; Wu YL(吴毓林)
刊名	J. Chem. Soc.-Perkin Trans. 1
	1999
页码	1189-1191
ISSN号	0300-922X
其他题名	以缩酮为烷化剂的付－克烷化反应的首例：合成苯并－8－氧双环[3.2.1]辛烷环体系的简捷方法
通讯作者	伍贻康
英文摘要	A novel acid-catalyzed intramolecular Friedel -Crafts alkylation(cyclization) using a spiroketal as electrophile leading to the otherwise not easily accessible benzene-fused 8-oxabicyclo[3.2.1]octane ring system in synthetically useful yields is reported. Slightly more than one equivalent of BF+3.Oet=2 in THF at refluxing temperature are found to be the most satisfactory conditions to achieve the desiredcyclization. An electro-donating group para to the position where cyclization will take placegreatly facilitates the reactiion.
学科主题	有机化学
收录类别	SCI
原文出处	http://dx.doi.org/10.1039/a900692c
语种	英语
公开日期	2013-01-17
内容类型	期刊论文
源URL	[http://202.127.28.38/handle/331003/13954]
专题	上海有机化学研究所_生命有机化学国家重点实验室
推荐引用方式 GB/T 7714	Fan JF,Wu YK,Wu YL. First examples of Friedel-Crafts alkylation using ketals as alkylating agents: an expeditious access to the benzene-fused8-oxabicyclo[3.2.1]octanering system.[J]. J. Chem. Soc.-Perkin Trans. 1,1999:1189-1191.
APA	范俊发,伍贻康,&吴毓林.(1999).First examples of Friedel-Crafts alkylation using ketals as alkylating agents: an expeditious access to the benzene-fused8-oxabicyclo[3.2.1]octanering system..J. Chem. Soc.-Perkin Trans. 1,1189-1191.
MLA	范俊发,et al."First examples of Friedel-Crafts alkylation using ketals as alkylating agents: an expeditious access to the benzene-fused8-oxabicyclo[3.2.1]octanering system.".J. Chem. Soc.-Perkin Trans. 1 (1999):1189-1191.