First examples of Friedel-Crafts alkylation using ketals as alkylating agents: an expeditious access to the benzene-fused8-oxabicyclo[3.2.1]octanering system. | |
Fan JF(范俊发) ; Wu YK(伍贻康) ; Wu YL(吴毓林) | |
刊名 | J. Chem. Soc.-Perkin Trans. 1
![]() |
1999 | |
页码 | 1189-1191 |
ISSN号 | 0300-922X |
其他题名 | 以缩酮为烷化剂的付-克烷化反应的首例:合成苯并-8-氧双环[3.2.1]辛烷环体系的简捷方法 |
通讯作者 | 伍贻康 |
英文摘要 | A novel acid-catalyzed intramolecular Friedel -Crafts alkylation(cyclization) using a spiroketal as electrophile leading to the otherwise not easily accessible benzene-fused 8-oxabicyclo[3.2.1]octane ring system in synthetically useful yields is reported. Slightly more than one equivalent of BF+3.Oet=2 in THF at refluxing temperature are found to be the most satisfactory conditions to achieve the desiredcyclization. An electro-donating group para to the position where cyclization will take placegreatly facilitates the reactiion. |
学科主题 | 有机化学 |
收录类别 | SCI |
原文出处 | http://dx.doi.org/10.1039/a900692c |
语种 | 英语 |
公开日期 | 2013-01-17 |
内容类型 | 期刊论文 |
源URL | [http://202.127.28.38/handle/331003/13954] ![]() |
专题 | 上海有机化学研究所_生命有机化学国家重点实验室 |
推荐引用方式 GB/T 7714 | Fan JF,Wu YK,Wu YL. First examples of Friedel-Crafts alkylation using ketals as alkylating agents: an expeditious access to the benzene-fused8-oxabicyclo[3.2.1]octanering system.[J]. J. Chem. Soc.-Perkin Trans. 1,1999:1189-1191. |
APA | 范俊发,伍贻康,&吴毓林.(1999).First examples of Friedel-Crafts alkylation using ketals as alkylating agents: an expeditious access to the benzene-fused8-oxabicyclo[3.2.1]octanering system..J. Chem. Soc.-Perkin Trans. 1,1189-1191. |
MLA | 范俊发,et al."First examples of Friedel-Crafts alkylation using ketals as alkylating agents: an expeditious access to the benzene-fused8-oxabicyclo[3.2.1]octanering system.".J. Chem. Soc.-Perkin Trans. 1 (1999):1189-1191. |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论