Force spectroscopy of single receptor-ligand bond using an optical trap

	Force spectroscopy of single receptor-ligand bond using an optical trap
	Zhang Y(章燕); Sun GY(孙淦云); Li N(李宁); Huo B(霍波); Lv SQ(吕守芹); Long M(龙勉); Zhang, Y.
	2009
会议名称	2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
会议日期	November 2, 2009 - November 6, 2009
会议地点	Shanghai, China
关键词	Bond dissociation Force spectroscopy Low loading Novel methods Optical trap Receptor-ligand bonds Receptor-ligand interactions Thermal fluctuations Unbinding transitions
通讯作者	Zhang, Y.
中文摘要	Here we developed an thermal fluctuation assay using optical trap technique, which enables to visualize consecutive binding-unbinding transition and to unravel the bond dissociation at low spring cosntant and low loading rate. This novel method provided further understandings in monitoring biophysics of receptor-ligand interactions. ©2009 Optical Society of America.
收录类别	EI
会议录	2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009
语种	英语
ISBN号	9781557528773
内容类型	会议论文
源URL	[http://dspace.imech.ac.cn/handle/311007/60461]
专题	力学研究所_国家微重力实验室
通讯作者	Zhang, Y.
推荐引用方式 GB/T 7714	Zhang Y,Sun GY,Li N,et al. Force spectroscopy of single receptor-ligand bond using an optical trap[C]. 见:2009 Asia Communications and Photonics Conference and Exhibition, ACP 2009. Shanghai, China. November 2, 2009 - November 6, 2009.