Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum

	Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum
	Zhao, Jian-Qiang 1; Wang, Yan-Ming 2,3; Yang, Yan-Long 4; Zeng, Ying 4; Wang, Qi-Lan 1; Shao, Yun 1; Mei, Li-Juan 1; Shi, Yan-Ping 2,3; Tao, Yan-Duo 1
刊名	food chemistry
	2017-07-15
卷号	227 页码:93-101
关键词	Nitraria tangutorum Glucose-derived beta-carbolines Antioxidants alpha-Glucosidase inhibitory
英文摘要	nitraria tangutorum bor., having edible berries, is valued for reputed health benefits in qinghai-tibet plateau. the phytochemical research on the fruit juice of n. tangutorum led to the isolation of twenty-six compounds including five new compounds, tangutorids a-d (1, 2, 3a, and 3b), and (3e,5e)-7-o-beta-gluco syl-4-(2-methoxy-2-oxoethyl)hepta-3,5-dienoic acid (15). the structures of these compounds were elucidated through comprehensive spectroscopic analyses. tangutorids a-f were the first examples of glucose-derived beta-carbolines from natural products. the biogenetic pathways of 1-8 were proposed to involve pictet-spengler reactions and described starting from the co-isolated tryptophan (10) and corresponding aldehydes. all isolates were evaluated for their antioxidant and alpha-glucosidase inhibitory activities. compounds 21, 22, and 24 showed antioxidant activity with sc50 values ranging from 12.2 +/- 1.9 to 30.4 +/- 2.7 mu g/ml, and compound 1 showed strong alpha-glucosidase inhibitory effect with ic50 value of 63.3 +/- 4.6 mu g/ml. (c) 2017 elsevier ltd. all rights reserved.
WOS标题词	science & technology ; physical sciences ; life sciences & biomedicine
类目[WOS]	chemistry, applied ; food science & technology ; nutrition & dietetics
研究领域[WOS]	chemistry ; food science & technology ; nutrition & dietetics
关键词[WOS]	beta-carboline alkaloids ; alcoholic beverages ; acid ; constituents ; tryptophan ; glycosides ; plants ; ester ; foods
收录类别	SCI
语种	英语
WOS记录号	WOS:000396957100013
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6807]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 4.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Jian-Qiang,Wang, Yan-Ming,Yang, Yan-Long,et al. Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum[J]. food chemistry,2017,227:93-101.
APA	Zhao, Jian-Qiang.,Wang, Yan-Ming.,Yang, Yan-Long.,Zeng, Ying.,Wang, Qi-Lan.,...&Tao, Yan-Duo.(2017).Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum.food chemistry,227,93-101.
MLA	Zhao, Jian-Qiang,et al."Isolation and identification of antioxidant and alpha-glucosidase inhibitory compounds from fruit juice of Nitraria tangutorum".food chemistry 227(2017):93-101.