Comparative study of 17 β-estradiol on endocrine disruption and biotransformation in fingerlings and juveniles of Japanese sea bass Lateolabrax japonicus | |
Thilagam, Harikrishnan ; Gopalakrishnan, Singaram ; Bo, Jun ; Wang, Ke-Jian ; Bo J(薄军) ; Wang KJ(王克坚) | |
刊名 | http://dx.doi.org/10.1016/j.marpolbul.2014.05.024
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2014 | |
关键词 | Bioconversion Brain Cortisol Fish |
英文摘要 | Estrogenic contaminants in the aquatic environment are associated with endocrine disruption and feminization in fish. The effects of endocrine disrupting chemicals (EDCs) on fish have been well documented. However, very few studies have focused on 17 β-estradiol (E2) and its effects on endocrine system and biotransformation in a single prolonged exposure. This study investigated changes in the levels of serotonin (5-hydroxytryptamine) and acetyl choline esterase (AchE) in brain, cortisol in plasma and Ethoxyresorufin-O-deethylase (EROD) activity in gill of two different size groups (fingerlings and juveniles) of Japanese sea bass (Lateolabrax japonicus) upon exposure to two sub-lethal concentrations (200 and 2000 ng L-1) of E2 for 30d. The results indicate that cortisol level and EROD activity significantly increased in both groups, whereas serotonin level increased in juveniles and decreased in fingerlings due to E2 exposure. The correlation analysis revealed that E2 significantly affected the endocrine and biotransformation systems in both age groups. ? 2014 Elsevier Ltd. |
语种 | 英语 |
出版者 | Elsevier Ltd |
内容类型 | 期刊论文 |
源URL | [http://dspace.xmu.edu.cn/handle/2288/89950] ![]() |
专题 | 环境生态-已发表论文 |
推荐引用方式 GB/T 7714 | Thilagam, Harikrishnan,Gopalakrishnan, Singaram,Bo, Jun,et al. Comparative study of 17 β-estradiol on endocrine disruption and biotransformation in fingerlings and juveniles of Japanese sea bass Lateolabrax japonicus[J]. http://dx.doi.org/10.1016/j.marpolbul.2014.05.024,2014. |
APA | Thilagam, Harikrishnan,Gopalakrishnan, Singaram,Bo, Jun,Wang, Ke-Jian,薄军,&王克坚.(2014).Comparative study of 17 β-estradiol on endocrine disruption and biotransformation in fingerlings and juveniles of Japanese sea bass Lateolabrax japonicus.http://dx.doi.org/10.1016/j.marpolbul.2014.05.024. |
MLA | Thilagam, Harikrishnan,et al."Comparative study of 17 β-estradiol on endocrine disruption and biotransformation in fingerlings and juveniles of Japanese sea bass Lateolabrax japonicus".http://dx.doi.org/10.1016/j.marpolbul.2014.05.024 (2014). |
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