Structural Bioinformatics-Based Identification of EGFR Inhibitor Gefitinib as a Putative Lead Compound for BACE

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	Structural Bioinformatics-Based Identification of EGFR Inhibitor Gefitinib as a Putative Lead Compound for BACE
	Niu, Mingshan ; Hu, Jin ; Wu, Sijin ; Zhang, Xiaoe ; Xu, Huaxi ; Zhang, Yunwu ; Zhang, Jie ; Yang, Yongliang ; Xu HX(许华曦) ; Zhang YW(张云武) ; Zhang J(张杰)
刊名	http://dx.doi.org/10.1111/cbdd.12200
	2014
关键词	BETA-SECRETASE ENZYME ALZHEIMERS-DISEASE DRUG DISCOVERY PROTEIN THERAPEUTICS
英文摘要	Fundamental Research Funds for the Central Universities [DUT11SM12]; National Science Foundation in China, Medical Board Oncology Department [81000975]; -secretase (BACE-1) is a potential target for the treatment of Alzheimer's disease (AD). Despite its potential, only few compounds targeting BACE have entered the clinical trials. Herein, we describe the identification of Gefitinib as a potential lead com
语种	英语
出版者	WILEY-BLACKWELL
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/93717]
专题	医学院－已发表论文
推荐引用方式 GB/T 7714	Niu, Mingshan,Hu, Jin,Wu, Sijin,et al. Structural Bioinformatics-Based Identification of EGFR Inhibitor Gefitinib as a Putative Lead Compound for BACE[J]. http://dx.doi.org/10.1111/cbdd.12200,2014.
APA	Niu, Mingshan.,Hu, Jin.,Wu, Sijin.,Zhang, Xiaoe.,Xu, Huaxi.,...&张杰.(2014).Structural Bioinformatics-Based Identification of EGFR Inhibitor Gefitinib as a Putative Lead Compound for BACE.http://dx.doi.org/10.1111/cbdd.12200.
MLA	Niu, Mingshan,et al."Structural Bioinformatics-Based Identification of EGFR Inhibitor Gefitinib as a Putative Lead Compound for BACE".http://dx.doi.org/10.1111/cbdd.12200 (2014).