The controlled release study of Vincristine Sulfate | |
Sun, Y. ; Xu, L. ; Zhang, Q. Q. ; Zhou, H. Y. ; Zhang QQ(张其清) | |
2003 | |
关键词 | VCR collagen HPLC drug delivery system |
英文摘要 | We prepared microspheres of Vincristine Sulfate (VCR) through drying-from-oil method, then mixed the microspheres into 0.7% collagen swelling solution to prepare emulsion, spread the emulsion on plate to form film by frozen-dry method. The film was cross-linked and sterilized, then planted into the site of tumor and expected to release at steady speed. We measured the release of VCR in vivo and in vitro by HPLC. The results demonstrated that VCR controlled release films release at approximate steady speed in 15 days. |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://dspace.xmu.edu.cn/handle/2288/71361] |
专题 | 医学院-已发表论文 |
推荐引用方式 GB/T 7714 | Sun, Y.,Xu, L.,Zhang, Q. Q.,et al. The controlled release study of Vincristine Sulfate[J],2003. |
APA | Sun, Y.,Xu, L.,Zhang, Q. Q.,Zhou, H. Y.,&张其清.(2003).The controlled release study of Vincristine Sulfate.. |
MLA | Sun, Y.,et al."The controlled release study of Vincristine Sulfate".(2003). |
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