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	A PDF-Based Classification of Gait Cadence Patterns in Patients with Amyotrophic Lateral Sclerosis
	Wu, Y. F. ; Wu YF(吴云峰) ; Ng, S. C.
	2010
关键词	RADIAL-BASIS FUNCTIONS VIBROARTHROGRAPHIC SIGNALS PARAMETERS ALS
英文摘要	Amyotrophic lateral sclerosis (ALS) is a type of neurological disease due to the degeneration of motor neurons. During the course of such a progressive disease, it would be difficult for ALS patients to regulate normal locomotion, so that the gait stability becomes perturbed. This paper presents a pilot statistical study on the gait cadence (or stride interval) in ALS, based on the statistical analysis method. The probability density functions (PDFs) of stride interval were first estimated with the nonparametric Parzen-window method. We computed the mean of the left-foot stride interval and the modified Kullback-Leibler divergence (MKLD) from the PDFs estimated. The analysis results suggested that both of these two statistical parameters were significantly altered in ALS, and the least-squares support vector machine (LS-SVM) may effectively distinguish the stride patterns between the ALS patients and healthy controls, with an accurate rate of 82.8% and an area of 0.87 under the receiver operating characteristic curve.
语种	英语
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/70747]
专题	信息技术－已发表论文
推荐引用方式 GB/T 7714	Wu, Y. F.,Wu YF,Ng, S. C.. A PDF-Based Classification of Gait Cadence Patterns in Patients with Amyotrophic Lateral Sclerosis[J],2010.
APA	Wu, Y. F.,吴云峰,&Ng, S. C..(2010).A PDF-Based Classification of Gait Cadence Patterns in Patients with Amyotrophic Lateral Sclerosis..
MLA	Wu, Y. F.,et al."A PDF-Based Classification of Gait Cadence Patterns in Patients with Amyotrophic Lateral Sclerosis".(2010).

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