Capillary electrochromatographic separation of enantiomers on chemically bonded type of cellulose derivative chiral stationary phases with a positively charged spacer

	Capillary electrochromatographic separation of enantiomers on chemically bonded type of cellulose derivative chiral stationary phases with a positively charged spacer
	Chen, XM; Jin, WH; Qin, F; Liu, YQ; Zou, HF; Guo, BC
刊名	electrophoresis
	2003-08-01
卷号	24 期号:15 页码:2559-2566
关键词	capillary electrochromatography cellulose derivative chiral stationary phase
产权排序	1;1
英文摘要	positively charged chiral stationary phases (csps) were prepared for capillary electrochromatography (cec) separation of enantiomers by chemically immobilizing cellulose derivatives onto diethylenetriaminopropylated silica (deaps) with tolylene-2,4-diisocyanate (tdi) as a spacer reagent. anodic electroosmotic mobility was observed in both nonaqueous and aqueous mobile phases due to the positively charged amines on the surface of the prepared csps. for comparison, the traditionally used 3-aminopropyl silica (aps) was also adopted as the base material instead of deaps to prepare csp. it was observed that the eof on the deaps-based csp was 18%-60% higher than that on the aps-based csp under nonaqueous mobile phase conditions. separation of enantiomers in cec was performed on the positively charged csps with the nonaqueous mobile phases of pure ethanol or mixture of hexane-alcohol and the aqueous phases of acetonitrile-water or 95% ethanol. fast separation of enantiomers was achieved on the newly prepared csps.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	performance liquid-chromatography ; silica-gel ; enantioseparations ; size ; tris(3,5-dichlorophenylcarbamate) ; pore
收录类别	SCI
原文出处	true
语种	英语
WOS记录号	WOS:000184932400019
公开日期	2010-11-30
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/83423]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China
推荐引用方式 GB/T 7714	Chen, XM,Jin, WH,Qin, F,et al. Capillary electrochromatographic separation of enantiomers on chemically bonded type of cellulose derivative chiral stationary phases with a positively charged spacer[J]. electrophoresis,2003,24(15):2559-2566.
APA	Chen, XM,Jin, WH,Qin, F,Liu, YQ,Zou, HF,&Guo, BC.(2003).Capillary electrochromatographic separation of enantiomers on chemically bonded type of cellulose derivative chiral stationary phases with a positively charged spacer.electrophoresis,24(15),2559-2566.
MLA	Chen, XM,et al."Capillary electrochromatographic separation of enantiomers on chemically bonded type of cellulose derivative chiral stationary phases with a positively charged spacer".electrophoresis 24.15(2003):2559-2566.