Multi-Strain Infections and 'Relapse' of Leucocytozoon sabrazesi Gametocytes in Domestic Chickens in Southern China

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	Multi-Strain Infections and 'Relapse' of Leucocytozoon sabrazesi Gametocytes in Domestic Chickens in Southern China
	Zhao, Wenting ; Cai, Baowei ; Qi, Yanwei ; Liu, Shengfa ; Hong, Lingxian ; Lu, Mingke ; Chen, Xin ; Qiu, Chunhui ; Peng, Wenfeng ; Li, Jian ; Su, Xin-zhuan ; Liu SF(刘升发) ; Lu MK(卢明科) ; Chen X(陈鑫) ; Peng WF(彭文峰) ; Li J(李剑)
刊名	http://dx.doi.org/10.1371/journal.pone.0094877
	2014-04-11
关键词	AVIAN BLOOD PARASITES MIXED INFECTIONS PLASMODIUM-VIVAX IN-VITRO PREVALENCE BIRDS QUANTIFICATION DIVERSITY MALARIA FOREST
英文摘要	National Science Foundation of China [81201324, 81271858]; Project 111 of the State Bureau of Foreign Experts; Ministry of Education of China [B06016]; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health; Leucocytozoon parasites infect many species of avian hosts, including domestic chicken, and can inflict heavy economic loss to he poultry industry. Although the prevalence and distribution of two Leucocytozoon species (L. sabrazesi and L. caulleryi) have been reported in China previously, there are many questions related to the parasite infection that remain unanswered, including population diversity and transmission dynamics in domestic chickens. Here we surveyed chicken blood samples from even sites in four provinces of China to identify Leucocytozoon infection, characterized Parasite diversity within individual infected hosts and between sampling sites, and investigated the dynamics of gametocytemia in chickens over time. We found high infection rates in three of the seven sites. Clustering parasite sequences of the mitochondrial cytochrome oxidase III (coxIII) and cytochrome b (cytb) genes showed lack of grouping according to geographic origins and individual hosts carrying large numbers of L. sabrazesi strains Monitoring gametocytemia in blood samples from infected showed 'relapse' or persistence of low-level gametocytemia for 4-5 months, which could be explored as sting drugs against liver stages of Apicomplexan parasites. This study provides important information on population diversity and transmission dynamics of L. sabrazesi and for disease control.
语种	英语
出版者	PUBLIC LIBRARY SCIENCE
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/90796]
专题	生命科学－已发表论文
推荐引用方式 GB/T 7714	Zhao, Wenting,Cai, Baowei,Qi, Yanwei,et al. Multi-Strain Infections and 'Relapse' of Leucocytozoon sabrazesi Gametocytes in Domestic Chickens in Southern China[J]. http://dx.doi.org/10.1371/journal.pone.0094877,2014.
APA	Zhao, Wenting.,Cai, Baowei.,Qi, Yanwei.,Liu, Shengfa.,Hong, Lingxian.,...&李剑.(2014).Multi-Strain Infections and 'Relapse' of Leucocytozoon sabrazesi Gametocytes in Domestic Chickens in Southern China.http://dx.doi.org/10.1371/journal.pone.0094877.
MLA	Zhao, Wenting,et al."Multi-Strain Infections and 'Relapse' of Leucocytozoon sabrazesi Gametocytes in Domestic Chickens in Southern China".http://dx.doi.org/10.1371/journal.pone.0094877 (2014).