Differential expression and anti-oxidant function of glutathione peroxidase 3 in mouse uterus during decidualization

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	Differential expression and anti-oxidant function of glutathione peroxidase 3 in mouse uterus during decidualization
	Xu, Xiu ; Leng, Jing-Yu ; Gao, Fei ; Zhao, Zhen-Ao ; Deng, Wen-Bo ; Liang, Xiao-Huan ; Zhang, Yi-Juan ; Zhang, Zhi-Rong ; Li, Ming ; Sha, Ai-Guo ; Yang, Zeng-Ming ; Gao F(高飞) ; Yang ZM(杨增明)
刊名	http://dx.doi.org/10.1016/j.febslet.2014.02.043
	2014-05-02
关键词	ENDOMETRIAL STROMAL CELLS MESSENGER-RIBONUCLEIC-ACID IN-VITRO DECIDUALIZATION EMBRYO IMPLANTATION EARLY-PREGNANCY BINDING PROTEIN-1 PROLACTIN GENES ADENOCARCINOMA HYDROPEROXIDE
英文摘要	National Basic Research Program of China [2011CB944402, 2013CB910803]; National Natural Science Foundation of China [31272263, 31071276]; Glutathione peroxidase 3 (GPX3) is an important member of antioxidant enzymes for reducing reactive oxygen species and maintaining the oxygen balance. Gpx3 mRNA is strongly expressed in decidual cells from days 5 to 8 of pregnancy. After pregnant mice are treated with GPX inhibitor for 3 days, pregnancy rate is significantly reduced. Progesterone stimulates Gpx3 expression through PR/HIF1 alpha in mouse endometrial stromal cells. In the decidua, the high level of GPX3 expression is closely associated with the reduction of hydrogen peroxide (H2O2). Based on our data, GPX3 may play a major role in reducing H2O2 during decidualization. (C) 2014 Federation of European Biochemical Societies. Published by Elsevier B. V. All rights reserved.
语种	英语
出版者	ELSEVIER SCIENCE BV
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/90784]
专题	生命科学－已发表论文
推荐引用方式 GB/T 7714	Xu, Xiu,Leng, Jing-Yu,Gao, Fei,et al. Differential expression and anti-oxidant function of glutathione peroxidase 3 in mouse uterus during decidualization[J]. http://dx.doi.org/10.1016/j.febslet.2014.02.043,2014.
APA	Xu, Xiu.,Leng, Jing-Yu.,Gao, Fei.,Zhao, Zhen-Ao.,Deng, Wen-Bo.,...&杨增明.(2014).Differential expression and anti-oxidant function of glutathione peroxidase 3 in mouse uterus during decidualization.http://dx.doi.org/10.1016/j.febslet.2014.02.043.
MLA	Xu, Xiu,et al."Differential expression and anti-oxidant function of glutathione peroxidase 3 in mouse uterus during decidualization".http://dx.doi.org/10.1016/j.febslet.2014.02.043 (2014).