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Development of the Hepatitis E Vaccine: From Bench to Field
Zhang, Jun ; Shih, James WaiKuo ; Wu, Ting ; Li, Shao-Wei ; Xia, Ning-Shao ; Zhang J(张军) ; Wu T(吴婷) ; Li SW(李少伟) ; Xia NS(夏宁邵)
刊名http://dx.doi.org/10.1055/s-0033-1338116
2013
关键词E VIRUS HEV INDUCED LIVER-INJURY NON-B HEPATITIS RHESUS-MONKEYS BLOOD-DONORS CAPSID PROTEIN PROTECTIVE EFFICACY INSECT CELLS MONOCLONAL-ANTIBODIES RECOMBINANT VACCINE
英文摘要National Science Fund for Distinguished Young Scholars [30925030]; National Major Scientific and Technological Special Project for "Significant New Drugs Development [2013ZX09101017]; Along with the improvement of diagnostic techniques, hepatitis E has attracted increasing awareness in recent years. Hepatitis E virus infection leads to high mortality in pregnant women and patients with underlying liver disease. Several hepatitis E vaccine candidates have been designed and have proved their efficacy in animal models; two candidates have successfully undergone clinical trials. Having proved safe and effective in a large phase Ill trials, an Escherichia coli expressed particulate protein, HEV 239, has been registered in China and is now available for use in China.
语种英语
出版者THIEME MEDICAL PUBL INC
内容类型期刊论文
源URL[http://dspace.xmu.edu.cn/handle/2288/90612]  
专题生命科学-已发表论文
推荐引用方式
GB/T 7714
Zhang, Jun,Shih, James WaiKuo,Wu, Ting,et al. Development of the Hepatitis E Vaccine: From Bench to Field[J]. http://dx.doi.org/10.1055/s-0033-1338116,2013.
APA Zhang, Jun.,Shih, James WaiKuo.,Wu, Ting.,Li, Shao-Wei.,Xia, Ning-Shao.,...&夏宁邵.(2013).Development of the Hepatitis E Vaccine: From Bench to Field.http://dx.doi.org/10.1055/s-0033-1338116.
MLA Zhang, Jun,et al."Development of the Hepatitis E Vaccine: From Bench to Field".http://dx.doi.org/10.1055/s-0033-1338116 (2013).
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