Development of the Hepatitis E Vaccine: From Bench to Field | |
Zhang, Jun ; Shih, James WaiKuo ; Wu, Ting ; Li, Shao-Wei ; Xia, Ning-Shao ; Zhang J(张军) ; Wu T(吴婷) ; Li SW(李少伟) ; Xia NS(夏宁邵) | |
刊名 | http://dx.doi.org/10.1055/s-0033-1338116
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2013 | |
关键词 | E VIRUS HEV INDUCED LIVER-INJURY NON-B HEPATITIS RHESUS-MONKEYS BLOOD-DONORS CAPSID PROTEIN PROTECTIVE EFFICACY INSECT CELLS MONOCLONAL-ANTIBODIES RECOMBINANT VACCINE |
英文摘要 | National Science Fund for Distinguished Young Scholars [30925030]; National Major Scientific and Technological Special Project for "Significant New Drugs Development [2013ZX09101017]; Along with the improvement of diagnostic techniques, hepatitis E has attracted increasing awareness in recent years. Hepatitis E virus infection leads to high mortality in pregnant women and patients with underlying liver disease. Several hepatitis E vaccine candidates have been designed and have proved their efficacy in animal models; two candidates have successfully undergone clinical trials. Having proved safe and effective in a large phase Ill trials, an Escherichia coli expressed particulate protein, HEV 239, has been registered in China and is now available for use in China. |
语种 | 英语 |
出版者 | THIEME MEDICAL PUBL INC |
内容类型 | 期刊论文 |
源URL | [http://dspace.xmu.edu.cn/handle/2288/90612] ![]() |
专题 | 生命科学-已发表论文 |
推荐引用方式 GB/T 7714 | Zhang, Jun,Shih, James WaiKuo,Wu, Ting,et al. Development of the Hepatitis E Vaccine: From Bench to Field[J]. http://dx.doi.org/10.1055/s-0033-1338116,2013. |
APA | Zhang, Jun.,Shih, James WaiKuo.,Wu, Ting.,Li, Shao-Wei.,Xia, Ning-Shao.,...&夏宁邵.(2013).Development of the Hepatitis E Vaccine: From Bench to Field.http://dx.doi.org/10.1055/s-0033-1338116. |
MLA | Zhang, Jun,et al."Development of the Hepatitis E Vaccine: From Bench to Field".http://dx.doi.org/10.1055/s-0033-1338116 (2013). |
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