Cytotoxic and antimicrobial metabolites from marine lignicolous fungi, Diaporthe sp

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	Cytotoxic and antimicrobial metabolites from marine lignicolous fungi, Diaporthe sp
	Lin,X ; Zheng,ZH ; Su,WJ ; Huang,YJ ; Wang,JF ; Fang,MJ ; Huang YJ(黄耀坚)
刊名	http://dx.doi.org/10.1016/j.femsle.2005.07.025
	2005-10-01
关键词	PHOMOPSIDIN
英文摘要	A new compound (1), named diaporthelactone, together with two known compounds (2 and 3) were isolated from the culture of Diaporthe sp., a marine fungus growing in the submerged rotten leaves of Kandelia candel in the mangrove nature conservation areas of Fugong, Fujian Province of China. The new compound was elucidated to be 1,3-dihydro-4-methoxy-7methyl-3-oxo-5-isobenzofuran-carboxyaldehyde (1), which showed cytotoxic activity against KB and Raji cell lines (IC50 6.25 and 5.51 mu G mL(-1), respectively). Two known compounds, 7-methoxy-4,6-dimethyl-3H-isobenzofuran-1-one (2) and mycoepoxydiene (3), were also demonstrated to exhibit cytotoxic activities for the first time. All three compounds were assessed for antimicrobial activity. (c) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.
语种	英语
出版者	ELSEVIER SCIENCE BV
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/90441]
专题	生命科学－已发表论文
推荐引用方式 GB/T 7714	Lin,X,Zheng,ZH,Su,WJ,et al. Cytotoxic and antimicrobial metabolites from marine lignicolous fungi, Diaporthe sp[J]. http://dx.doi.org/10.1016/j.femsle.2005.07.025,2005.
APA	Lin,X.,Zheng,ZH.,Su,WJ.,Huang,YJ.,Wang,JF.,...&黄耀坚.(2005).Cytotoxic and antimicrobial metabolites from marine lignicolous fungi, Diaporthe sp.http://dx.doi.org/10.1016/j.femsle.2005.07.025.
MLA	Lin,X,et al."Cytotoxic and antimicrobial metabolites from marine lignicolous fungi, Diaporthe sp".http://dx.doi.org/10.1016/j.femsle.2005.07.025 (2005).