The p38 signal transduction pathway - Activation and function | |
Ono, K. ; Han, J. H. ; Han JH(韩家淮) | |
2000 | |
关键词 | MAPK p38 signalling |
英文摘要 | The p38 signalling transduction pathway, a Mitogen-activated protein (MAP) kinase pathway, plays an essential role in regulating many cellular processes including inflammation, cell differentiation, cell growth and death. Activation of p38 often through extracellular stimuli such as bacterial pathogens and cytokines, mediates signal transduction into the nucleus to turn on the responsive genes. p38 also transduces signals to other cellular components to execute different cellular responses. In this review, we summarize the characteristics of the major components of the p38 signalling transduction pathway and highlight the targets of this pathway and the physiological function of the p38 activation. (C) 2000 Elsevier Science Inc. All rights reserved. |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://dspace.xmu.edu.cn/handle/2288/65739] ![]() |
专题 | 生命科学-已发表论文 |
推荐引用方式 GB/T 7714 | Ono, K.,Han, J. H.,Han JH. The p38 signal transduction pathway - Activation and function[J],2000. |
APA | Ono, K.,Han, J. H.,&韩家淮.(2000).The p38 signal transduction pathway - Activation and function.. |
MLA | Ono, K.,et al."The p38 signal transduction pathway - Activation and function".(2000). |
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