| Basigin expression and hormonal regulation in the rat uterus during the peri-implantation period | |
| Xiao, L. J. ; Diao, H. L. ; Ma, X. H. ; Ding, N. Z. ; Kadomatsu, K. ; Muramatsu, T. ; Yang, Z. M. ; Yang ZM(杨增明) | |
| 2002 | |
| 关键词 | LEUKEMIA INHIBITORY FACTOR IMMUNOGLOBULIN SUPERFAMILY MEMBER ENDOMETRIAL STROMAL CELLS BLASTOCYST IMPLANTATION MOUSE UTERUS IN-VITRO DECIDUALIZATION DOMAIN LIF |
| 英文摘要 | Basigin is essential for fertilization and implantation. The aim of this study was to determine the expression and hormonal regulation of the basigin gene in the rat uterus during the peri-implantation period. Basigin mRNA was localized strongly in the luminal epithelium on day 1 of pregnancy and gradually decreased to a basal concentration from day 3 to day 5 of pregnancy. Basigin mRNA and protein were expressed strongly in the implanting blastocyst and primary decidua on day 6 of pregnancy. A similar expression pattern was also induced in the uterus after delayed implantation was terminated by oestrogen treatment and the embryo implanted, whereas expression was not detected during delayed implantation. Basigin expression was not detected on day 6 of pseudopregnancy. Basigin mRNA was expressed strongly in the decidua on days 7 and 8 of pregnancy. Furthermore, both basigin mRNA and protein were induced in the decidua during artificial decidualization. In addition, oestrogen stimulated strong expression of basigin mRNA in the uterine epithelium of ovariectomized rats. These findings indicate that basigin may play a role during implantation and decidualization in rats. |
| 语种 | 英语 |
| 内容类型 | 期刊论文 |
| 源URL | [http://dspace.xmu.edu.cn/handle/2288/65232]  |
| 专题 | 生命科学－已发表论文 |
| 推荐引用方式 GB/T 7714 | Xiao, L. J.,Diao, H. L.,Ma, X. H.,et al. Basigin expression and hormonal regulation in the rat uterus during the peri-implantation period[J],2002. |
| APA | Xiao, L. J..,Diao, H. L..,Ma, X. H..,Ding, N. Z..,Kadomatsu, K..,...&杨增明.(2002).Basigin expression and hormonal regulation in the rat uterus during the peri-implantation period.. |
| MLA | Xiao, L. J.,et al."Basigin expression and hormonal regulation in the rat uterus during the peri-implantation period".(2002). |
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