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	Seroprevalence of hepatitis E virus infection, rural southern People‘s Republic of China
	Li, RC ; Ge, SX ; Li, YP ; Zheng, YJ ; Nong, Y ; Guo, QS ; Zhang, J ; Ng, MH ; Xia, NS
	2006-09
关键词	NON-B HEPATITIS NON-A PHYLOGENETIC ANALYSIS UNITED-STATES GENETIC-HETEROGENEITY HEV INFECTION E VACCINE SWINE ANTIBODIES IDENTIFICATION
英文摘要	Genotype 4 hepatitis E virus (HEV) is the dominant cause of hepatitis E in the People's Republic of China; swine are the principal reservoir. Our study was conducted in 8 rural communities of southern China, where families keep pigs near their homes. Phylogenetic analysis showed that 23 of 24 concurrent virus isolates from this region are genotype 4 strains. Among the study populations, immunoglobulin G anti-HEV seroprevalence accumulated with age at approximate to 1% per year for persons <= 60 years of age. After age 30 years, seroprevalence increased at higher rates for male than for female study participants. The overall seroprevalence was 43% (range 25%-66%) among the communities. Infection rates were higher for participants between 25 and 29 years of age. The results suggest that HEV infection probably has been endemic in southern China for at least 60 years, with swine being the principal reservoir of human HEV infection in recent vears.
语种	英语
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/65088]
专题	生命科学－已发表论文
推荐引用方式 GB/T 7714	Li, RC,Ge, SX,Li, YP,et al. Seroprevalence of hepatitis E virus infection, rural southern People‘s Republic of China[J],2006.
APA	Li, RC.,Ge, SX.,Li, YP.,Zheng, YJ.,Nong, Y.,...&Xia, NS.(2006).Seroprevalence of hepatitis E virus infection, rural southern People‘s Republic of China..
MLA	Li, RC,et al."Seroprevalence of hepatitis E virus infection, rural southern People‘s Republic of China".(2006).

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