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	Hippo pathway in intestinal homeostasis and tumorigenesis
	Chen, Lanfen ; Qin, Funiu ; Qin FN(秦福牛) ; Deng, Xianming ; Avruch, Joseph ; Zhou, Dawang ; Zhou DW(周大旺)
	2012-04
关键词	Hippo/Mst1/2 YAP/Yorkie intestinal stem cells
英文摘要	The Hippo pathway plays a crucial role in controlling organ size by inhibiting cell proliferation and promoting cell death. Recent findings implicate that this pathway is involved in the process of intestinal regeneration and tumorigenesis. Here we summarize current studies for the function of the Hippo signaling pathway in intestinal homeostasis, regeneration and tumorigenesis, and the crosstalk between the Hippo signaling pathway and other major signaling pathways, i.e. Wnt, Notch and Jak/Stat signaling pathways in intestinal compartment.; China's 1000 Young Talents Program; 111 Project of The Ministration of Education of China [B06016]; Fundamental Research Funds for the Central Universities of China [2010111079]; National Natural Science Foundation of China [81101503]; Natural Science Foundation of Fujian [2011J05096]; RO1 awards [CA136567, DK17776]
语种	英语
出版者	HIGHER EDUCATION PRESS
内容类型	期刊论文
源URL	[http://dx.doi.org/10.1007/s13238-012-2913-9]
专题	生命科学－已发表论文
推荐引用方式 GB/T 7714	Chen, Lanfen,Qin, Funiu,Qin FN,et al. Hippo pathway in intestinal homeostasis and tumorigenesis[J],2012.
APA	Chen, Lanfen.,Qin, Funiu.,秦福牛.,Deng, Xianming.,Avruch, Joseph.,...&周大旺.(2012).Hippo pathway in intestinal homeostasis and tumorigenesis..
MLA	Chen, Lanfen,et al."Hippo pathway in intestinal homeostasis and tumorigenesis".(2012).

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