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	Karyopherins in nuclear transport of homeodomain proteins during development
	Ye, Wenduo ; Lin, Wenbo ; Tartakoff, Alan M. ; Tao, Tao ; Tao T(陶涛)
	2011-01-20
关键词	Homeodomain Homeoprotein Nuclear transport Importin alpha Karyopherin beta NLS NES Development Regulation
英文摘要	Homeodomain proteins are crucial transcription factors for cell differentiation, cell proliferation and organ development. Interestingly, their homeodomain signature structure is important for both their DNA-binding and their nucleocytoplasmic trafficking. The accurate nucleocytoplasmic distribution of these proteins is essential for their functions. We summarize information on (a) the roles of karyopherins for import and export of homeoproteins, (b) the regulation of their nuclear transport during development, and (c) the corresponding complexity of homeoprotein nucleocytoplasmic transport signals. This article is part of a Special Issue entitled: Regulation of Signaling and Cellular Fate through Modulation of Nuclear Protein Import. (C) 2011 Elsevier B.V. All rights reserved.; National Foundation of Science of China[30971669, 81071670]; Ministry of Science and Technology, China[2006AA02A310]; Ministry of Education, China[20090121110014]; Department of Science and Technology, Fujian Province China[2009I0026]; National Institutes of Health
语种	英语
出版者	ELSEVIER SCIENCE BV
内容类型	期刊论文
源URL	[http://dx.doi.org/doi:10.1016/j.bbamcr.2011.01.013]
专题	生命科学－已发表论文
推荐引用方式 GB/T 7714	Ye, Wenduo,Lin, Wenbo,Tartakoff, Alan M.,et al. Karyopherins in nuclear transport of homeodomain proteins during development[J],2011.
APA	Ye, Wenduo,Lin, Wenbo,Tartakoff, Alan M.,Tao, Tao,&陶涛.(2011).Karyopherins in nuclear transport of homeodomain proteins during development..
MLA	Ye, Wenduo,et al."Karyopherins in nuclear transport of homeodomain proteins during development".(2011).

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