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Receptor-interacting protein (RIP) kinase family
Zhang, Duanwu ; Lin, Juan ; Han, Jiahuai ; Han JH(韩家淮)
2010-04
关键词apoptosis kinase necrosis RIP TNF
英文摘要Receptor-interacting protein (RIP) kinases are a group of threonine/serine protein kinases with a relatively conserved kinase domain but distinct non-kinase regions. A number of different domain structures, such as death and caspase activation and recruitment domain (CARD) domains, were found in different RIP family members, and these domains should be keys in determining the specific function of each RIP kinase. It is known that RIP kinases participate in different biological processes, including those in innate immunity, but their downstream substrates are largely unknown. This review will give an overview of the structures and functions of RIP family members, and an update of recent progress in RIP kinase research. Cellular & Molecular Immunology (2010) 7, 243-249; doi:10.1038/cmi.2010.10; published online 12 April 2010
语种英语
出版者NATURE PUBLISHING GROUP
内容类型期刊论文
源URL[http://dx.doi.org/doi:10.1038/cmi.2010.10]  
专题生命科学-已发表论文
推荐引用方式
GB/T 7714
Zhang, Duanwu,Lin, Juan,Han, Jiahuai,et al. Receptor-interacting protein (RIP) kinase family[J],2010.
APA Zhang, Duanwu,Lin, Juan,Han, Jiahuai,&韩家淮.(2010).Receptor-interacting protein (RIP) kinase family..
MLA Zhang, Duanwu,et al."Receptor-interacting protein (RIP) kinase family".(2010).
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