Using HPLC retention parameters to estimate fish bioconcentration factors of organic compounds

	Using HPLC retention parameters to estimate fish bioconcentration factors of organic compounds
	Guo, RB ; Liang, XM ; Chen, JP ; Zhang, Q ; Wu, WZ ; Kettrup, A
刊名	journal of liquid chromatography & related technologies
	2004
卷号	27 期号:12 页码:1861-1873
关键词	retention parameters bioconcentration HPLC linear regression
产权排序	1;1
英文摘要	reversed-phase high performance liquid chromatography (rp-hplc) was employed to develop predictive models for fish bioconcentration factors (bcf) of organic compounds. estimation of bcf from rp-hplc retention parameters on octadecyl-bonded silica gel (ods), cyanopropyl-bonded silica gel (cn), and phenyl-bonded silica gel (ph) columns were investigated. the results show that, for a set of compounds belonging to different chemical classes, the cn stationary phase is the best one among the three columns and better than n-octanol/water model for bcf estimation. a multi-column rp-hplc model, using the retention parameters on the cn and ph columns as the variables of multiple linear regression equations, was further evaluated to estimate bcf of organic compounds belonging to different chemical classes, and the results show that the multi-column rp-hplc model is better than that of any single rp-hplc column for bcf estimation.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	phase liquid-chromatography ; solvation energy relationships ; water ; prediction ; soil ; coefficient ; toxicity ; models
收录类别	SCI
原文出处	true
语种	英语
WOS记录号	WOS:000222213700004
公开日期	2010-11-30
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/81619]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116011, Peoples R China 2.GSF Natl Res Ctr Environm & Hlth, Inst Ecol Chem, Neuherberg, Germany 3.Univ Munich, Lehrstuhl Okol Chem & Umweltanalyt, Weihenstephan, Germany
推荐引用方式 GB/T 7714	Guo, RB,Liang, XM,Chen, JP,et al. Using HPLC retention parameters to estimate fish bioconcentration factors of organic compounds[J]. journal of liquid chromatography & related technologies,2004,27(12):1861-1873.
APA	Guo, RB,Liang, XM,Chen, JP,Zhang, Q,Wu, WZ,&Kettrup, A.(2004).Using HPLC retention parameters to estimate fish bioconcentration factors of organic compounds.journal of liquid chromatography & related technologies,27(12),1861-1873.
MLA	Guo, RB,et al."Using HPLC retention parameters to estimate fish bioconcentration factors of organic compounds".journal of liquid chromatography & related technologies 27.12(2004):1861-1873.