One-Pot Synthesis of Pyrazoles through a Four-Step Cascade Sequence

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	One-Pot Synthesis of Pyrazoles through a Four-Step Cascade Sequence
	Hao, Lu ; Hong, Jun-Jie ; Zhu, Jun ; Zhan, Zhuang-Ping ; Zhu J(朱军) ; Zhan ZP(詹庄平)
刊名	http://dx.doi.org/10.1002/chem.201204322
	2013
关键词	SUBSTITUTED PYRAZOLES CHEMOSELECTIVE SYNTHESIS DENSITY FUNCTIONALS CHEMISTRY INHIBITORS LIGANDS AROMATIZATION CYCLIZATIONS HYDRAZONES DISCOVERY
英文摘要	National Natural Science Foundation of China [21072159, 21272190]; Program for Changjiang Scholars and Innovative Research Team in University; 973 Projects [2011CB935901]; A one-pot synthesis of 3,4,5- and 1,3,5-pyrazoles from tertiary propargylic alcohols and para-tolylsulfonohydrazide has been accomplished. The pyrazoles are formed through a four-step cascade sequence, including FeCl3-catalyzed propargylic substitution, aza-MeyerSchuster rearrangement, base-mediated 6electrocyclization, and thermal [1,5] sigmatropic shift. In this reaction, the 3,4,5- and 1,3,5-pyrazoles are produced selectively according to different substituents in the starting alcohols.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/89078]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Hao, Lu,Hong, Jun-Jie,Zhu, Jun,et al. One-Pot Synthesis of Pyrazoles through a Four-Step Cascade Sequence[J]. http://dx.doi.org/10.1002/chem.201204322,2013.
APA	Hao, Lu,Hong, Jun-Jie,Zhu, Jun,Zhan, Zhuang-Ping,朱军,&詹庄平.(2013).One-Pot Synthesis of Pyrazoles through a Four-Step Cascade Sequence.http://dx.doi.org/10.1002/chem.201204322.
MLA	Hao, Lu,et al."One-Pot Synthesis of Pyrazoles through a Four-Step Cascade Sequence".http://dx.doi.org/10.1002/chem.201204322 (2013).