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	ORGN 67-Flexible approaches for the asymmetric synthesis of bioactive alkaloids
	Huang, PQ ; Huang PQ(黄培强)
	2008-08-17
英文摘要	2-Substituted 3-hetero-substituted pyrrolidines/ piperidines and tetramic acids are sub-structures found in a number of bioactive natural products, drugs and drug candidates. In this talk, we shall present our recent studies on the development of chiral non-racemic cyclic imides-based synthetic methodology and the complementary N-a-carbanion synthons-based synthetic methodology for the asymmetric syntheses of naturally occurring or pharmaceutically interesting hydroxylated pyrrolidines, 2-pyrrolidinones, b-hydroxy-g-amino acids, and their higher homologous, as well as tetramic acid and tetramate derivatives via new chiral non-racemic synthons A ~ C; and the enantio-divergent syntheses of both enantiomers of the marine alkaloid haliclorensin and isohaliclorensin, a constituent of cytotoxic marine alkaloid halitulin.
语种	英语
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/64449]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Huang, PQ,Huang PQ. ORGN 67-Flexible approaches for the asymmetric synthesis of bioactive alkaloids[J],2008.
APA	Huang, PQ,&黄培强.(2008).ORGN 67-Flexible approaches for the asymmetric synthesis of bioactive alkaloids..
MLA	Huang, PQ,et al."ORGN 67-Flexible approaches for the asymmetric synthesis of bioactive alkaloids".(2008).

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