A flexible approach for the asymmetric synthesis of N-protected (R)-5-alkyl tetramates and (R)-5-alkyl tetramic acid derivatives | |
Huang, PQ ; Huang PQ(黄培强) ; Deng, J | |
刊名 | http://dx.doi.org/10.1055/s-2003-44968
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2004-02-02 | |
关键词 | NON-RACEMIC SILYLOXYPYRROLE ALPHA-AMINO-ACIDS ANTINEOPLASTIC AGENTS POLYFUNCTIONALIZED PYRROLIDINES STEREOSPECIFIC SYNTHESIS ACYLATION ANALOGS PYRROLIDINE-2,4-DIONES (+)-PREUSSIN ALKYLATIONS |
英文摘要 | A flexible two-step asymmetric approach to N-protected (R)-5-alkyl tetramates and (R)-5-alkyl tetramic acid derivatives is described. The method is based on the diastereoselective alkylation of (R)-phenylglycinol derived tetramates 7 and 8, which are the first synthetic equivalents to chiral nonracemic tetramate 5-carbanionic synthons A. |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://dspace.xmu.edu.cn/handle/2288/64422] ![]() |
专题 | 化学化工-已发表论文 |
推荐引用方式 GB/T 7714 | Huang, PQ,Huang PQ,Deng, J. A flexible approach for the asymmetric synthesis of N-protected (R)-5-alkyl tetramates and (R)-5-alkyl tetramic acid derivatives[J]. http://dx.doi.org/10.1055/s-2003-44968,2004. |
APA | Huang, PQ,黄培强,&Deng, J.(2004).A flexible approach for the asymmetric synthesis of N-protected (R)-5-alkyl tetramates and (R)-5-alkyl tetramic acid derivatives.http://dx.doi.org/10.1055/s-2003-44968. |
MLA | Huang, PQ,et al."A flexible approach for the asymmetric synthesis of N-protected (R)-5-alkyl tetramates and (R)-5-alkyl tetramic acid derivatives".http://dx.doi.org/10.1055/s-2003-44968 (2004). |
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