Bis-Lewis acids-catalyzed highly diastereoselective one-pot reductive dehydroxylation of chiral N,O-acetals

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	Bis-Lewis acids-catalyzed highly diastereoselective one-pot reductive dehydroxylation of chiral N,O-acetals
	Jiang, LJ ; Teng, B ; Zheng, JF ; Zheng JF(郑剑峰) ; Ye, JL ; Ye JL(叶剑良) ; Huang, PQ ; Huang PQ(黄培强)
刊名	http://dx.doi.org/10.1016/j.tet.2009.11.003
	2010-01-02
关键词	N-ACYLIMINIUM IONS BIFUNCTIONAL ASYMMETRIC CATALYSIS INTERMOLECULAR ADDITION-REACTIONS RACEMIC BICYCLIC LACTAMS ORGANIC-SYNTHESIS TETRAMIC ACIDS 2-SUBSTITUTED PYRROLIDINES ENANTIOSELECTIVE SYNTHESIS ISOINDOLINONE DERIVATIVES STEREOSELECTIVE-SYNTH
英文摘要	NSFC [20832005, 20602028]; Innovative Research Team in Science & Technology (University) in Fujian Province; A one-pot and highly diastereoselective method for the reductive dehydroxylation of three classes of heterocyclic N,O-acetals with general structure 4 is reported. The method features a 'two in one' concept, namely, by synergetic action of two complementary Lewis acids (BF.OEt2 and TiCl4), the bicyclic or tricyclic oxazololactams 5 were formed in situ and reductively cleaved to give the corresponding lactams 6 in a high-yielding and highly diastereoselective manner. (C) 2009 Elsevier Ltd. All rights reserved.
语种	英语
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/64414]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Jiang, LJ,Teng, B,Zheng, JF,et al. Bis-Lewis acids-catalyzed highly diastereoselective one-pot reductive dehydroxylation of chiral N,O-acetals[J]. http://dx.doi.org/10.1016/j.tet.2009.11.003,2010.
APA	Jiang, LJ.,Teng, B.,Zheng, JF.,郑剑峰.,Ye, JL.,...&黄培强.(2010).Bis-Lewis acids-catalyzed highly diastereoselective one-pot reductive dehydroxylation of chiral N,O-acetals.http://dx.doi.org/10.1016/j.tet.2009.11.003.
MLA	Jiang, LJ,et al."Bis-Lewis acids-catalyzed highly diastereoselective one-pot reductive dehydroxylation of chiral N,O-acetals".http://dx.doi.org/10.1016/j.tet.2009.11.003 (2010).