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Nanoprobes for in vitro diagnostics of cancer and infectious diseases
Chi, Xiaoqin ; Huang, Dengtong ; Zhao, Zhenghuan ; Zhou, Zijian ; Yin, Zhenyu ; Gao, Jinhao ; Gao JH(高锦豪)
刊名http://dx.doi.org/10.1016/j.biomaterials.2011.09.032
2012-01
关键词BIOFUNCTIONAL MAGNETIC NANOPARTICLES ENHANCED RAMAN-SCATTERING SURFACE-PLASMON RESONANCE PROTEIN-PROTEIN INTERACTIONS SEMICONDUCTOR QUANTUM DOTS GRAM-NEGATIVE BACTERIA CARBON NANOTUBES LIVE CELLS ENERGY-TRANSFER DRUG-DELIVERY
英文摘要National Natural Science Foundation of China [21021061, 81000662]; Fundamental Research Funds for the Central Universities [2010121012]; Research Funds for the Doctoral Program of Higher Education of China [20100121120009]; Program for New Century Excellent Talents in University [NCET-10-0709]; China Postdoctoral Science Foundation [20110490849]; The successful and explosive development of nanotechnology is significantly impacting the fields of biology and medicine. Among the spectacular developments of nanobiotechnology, interest has grown in the use of nanomaterials as nanoprobes for bioanalysis and diagnosis. Herein, we review state-of-the-art nanomaterial-based probes and discuss their applications in in vitro diagnostics (IVD) and challenges in bringing these fields together. Major classes of nanoprobes include quantum dots (QDs), plasmonic nanoparticles, magnetic nanoparticles, nanotubes, nanowires, and multifunctional nanomaterials. With the advantages of high volume/surface ratio, surface tailorability, multifunctionality, and intrinsic properties, nanoprobes have tremendous applications in the areas of biomarker discovery, diagnostics of infectious diseases, and cancer detection. The distinguishing features of nanoprobes for in vitro use, such as harmlessness, ultrasensitivity, multiplicity, and point-of-care use, will bring a bright future of nanodiagnosis. (C) 2011 Elsevier Ltd. All rights reserved.
语种英语
内容类型期刊论文
源URL[http://dspace.xmu.edu.cn/handle/2288/64338]  
专题化学化工-已发表论文
推荐引用方式
GB/T 7714
Chi, Xiaoqin,Huang, Dengtong,Zhao, Zhenghuan,et al. Nanoprobes for in vitro diagnostics of cancer and infectious diseases[J]. http://dx.doi.org/10.1016/j.biomaterials.2011.09.032,2012.
APA Chi, Xiaoqin.,Huang, Dengtong.,Zhao, Zhenghuan.,Zhou, Zijian.,Yin, Zhenyu.,...&高锦豪.(2012).Nanoprobes for in vitro diagnostics of cancer and infectious diseases.http://dx.doi.org/10.1016/j.biomaterials.2011.09.032.
MLA Chi, Xiaoqin,et al."Nanoprobes for in vitro diagnostics of cancer and infectious diseases".http://dx.doi.org/10.1016/j.biomaterials.2011.09.032 (2012).
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