Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates | |
Ding, J. J. ; Qian, N. ; Li, C. ; Qiao, R. Z. ; Zhao, Y. F. ; Zhao YF(赵玉芬) | |
2009 | |
关键词 | DNA MINOR-GROOVE ESI-MS CHARACTERISTICS POLYAMINE AMIDES RECOGNITION BINDING SPECTRA ANALOGS AZT DERIVATIVES ALKYLATION |
英文摘要 | The study of the dissociation of the protonated molecular species [M+H](+) and selected fragment ions allowed proposals for the main fragmentation pathways of the title compounds. The main fragments are formed by expelling a molecule of thymine, thymidine (d4T) or isopropyl. The most striking feature of the tandem mass (MS/MS) spectra is the cleavage of C-CO bonds between N-methylpyrrole and carbonyl groups in the presence of the amidine. Electrospray ionization is proven to be a good method for the structural characterization and identification of these kinds of compounds. Copyright (C) 2009 John Wiley & Sons, Ltd. |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://dspace.xmu.edu.cn/handle/2288/63750] ![]() |
专题 | 化学化工-已发表论文 |
推荐引用方式 GB/T 7714 | Ding, J. J.,Qian, N.,Li, C.,et al. Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates[J],2009. |
APA | Ding, J. J.,Qian, N.,Li, C.,Qiao, R. Z.,Zhao, Y. F.,&赵玉芬.(2009).Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates.. |
MLA | Ding, J. J.,et al."Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates".(2009). |
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