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Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates
Ding, J. J. ; Qian, N. ; Li, C. ; Qiao, R. Z. ; Zhao, Y. F. ; Zhao YF(赵玉芬)
2009
关键词DNA MINOR-GROOVE ESI-MS CHARACTERISTICS POLYAMINE AMIDES RECOGNITION BINDING SPECTRA ANALOGS AZT DERIVATIVES ALKYLATION
英文摘要The study of the dissociation of the protonated molecular species [M+H](+) and selected fragment ions allowed proposals for the main fragmentation pathways of the title compounds. The main fragments are formed by expelling a molecule of thymine, thymidine (d4T) or isopropyl. The most striking feature of the tandem mass (MS/MS) spectra is the cleavage of C-CO bonds between N-methylpyrrole and carbonyl groups in the presence of the amidine. Electrospray ionization is proven to be a good method for the structural characterization and identification of these kinds of compounds. Copyright (C) 2009 John Wiley & Sons, Ltd.
语种英语
内容类型期刊论文
源URL[http://dspace.xmu.edu.cn/handle/2288/63750]  
专题化学化工-已发表论文
推荐引用方式
GB/T 7714
Ding, J. J.,Qian, N.,Li, C.,et al. Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates[J],2009.
APA Ding, J. J.,Qian, N.,Li, C.,Qiao, R. Z.,Zhao, Y. F.,&赵玉芬.(2009).Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates..
MLA Ding, J. J.,et al."Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates".(2009).
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