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	Template effect of adenine-contained polymer nucleic acid analog on the coupled action of uridine by N-(O,O ‘-diisopropyl)phosphoryl alanine
	Zhao YF(赵玉芬)
	2001-10
关键词	phosphoryl amino acid nucleoside polymer nucleic acid analog template effect
英文摘要	The effect of poly [beta-(N-7-adeninyl) ethyl methacrylate] on the reaction of uridine with N-(O,O'-diisopropyl)phosphoryl alanine was studied. It was found that the adenine-contained polymer nucleic acid analog acted as a template to accelerate the coupled action of uridine by phosphoryl alanine. In the presence of the nucleic acid analog, the yield of uridyl-nucleotides and uridyl-oligonucleotides were increased significantly. The template effect of poly [beta-(N-7-adeninyl) ethyl methacrylate] showed a selectivity to the coupled action of uridine but not the adenosine. In addition, since the skeleton polymethacrylate did not show any catalytic effect, the template effect of poly [beta-(N-7-adeninyl) ethyl methacrylate] must the due to the adenine-bonded side chain.
语种	英语
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/63592]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Zhao YF. Template effect of adenine-contained polymer nucleic acid analog on the coupled action of uridine by N-(O,O ‘-diisopropyl)phosphoryl alanine[J],2001.
APA	赵玉芬.(2001).Template effect of adenine-contained polymer nucleic acid analog on the coupled action of uridine by N-(O,O ‘-diisopropyl)phosphoryl alanine..
MLA	赵玉芬."Template effect of adenine-contained polymer nucleic acid analog on the coupled action of uridine by N-(O,O ‘-diisopropyl)phosphoryl alanine".(2001).

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