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	Molecular aptamers for drug delivery
	Tan, Weihong（Hunan Univ, Coll Chem & Chem Engn） ; Wang, Hui（ Univ Florida, UF Genet Inst） ; Chen, Yan ; Zhang, Xiaobing（Hunan Univ, Coll Chem & Chem Engn） ; Zhu, Haizhen（Hunan Univ, Coll Chem & Chem Engn） ; Yang, Chaoyong ; Yang CY(杨朝勇) ; Yang, Ronghua（Hunan Univ, Coll Chem & Chem Engn） ; Liu, Chen（ Univ Florida, UF Genet Inst）
	2011-08-06
英文摘要	The active targeting of drugs in a cell-, tissue- or disease-specific manner represents a potentially powerful technology with widespread applications in medicine, including the treatment of cancers. Aptamers have properties such as high affinity and specificity for targets, easy chemical synthesis and modification, and rapid tissue penetration. They have become attractive molecules in diagnostics and therapeutics rivaling and, in some cases, surpassing other molecular probes, such as antibodies. In this review, we highlight the recent progress in aptamer-mediated delivery for therapeutics and disease-targeting based on aptamer integration with a variety of nanomaterials, such as gold nanorods, DNA micelles, DNA hydrogels and carbon nanotubes.; National Key Scientific Program of China[2011CB911000]; China National Grand Program[2009ZX10004-312]; National Institutes of Health[GM066137, GM079359, CA133086]
语种	英语
出版者	ELSEVIER SCIENCE LONDON
内容类型	期刊论文
源URL	[http://dx.doi.org/doi:10.1016/j.tibtech.2011.06.009]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Tan, Weihong,Wang, Hui,Chen, Yan,et al. Molecular aptamers for drug delivery[J],2011.
APA	Tan, Weihong.,Wang, Hui.,Chen, Yan.,Zhang, Xiaobing.,Zhu, Haizhen.,...&Liu, Chen.(2011).Molecular aptamers for drug delivery..
MLA	Tan, Weihong,et al."Molecular aptamers for drug delivery".(2011).

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