QQ客服 官方微博 反馈留言

	Asymmetric syntheses of protected (2S,3S,4S)-3-hydroxy-4-methylproline and 4 '-tert-butoxyamido-2 '-deoxythymidine
	Wei-Hua Meng ; Tian-Jun Wu ; Hong-Kui Zhang ; Zhang HK(张洪奎) ; Pei-Qiang Huang ; Huang PQ(黄培强)
	2004-11
英文摘要	Described herein is a versatile approach to (i) (2S,3S,4S)-3-hydroxy-4-methylproline 3, a constituent of echinocandins and related oligopeptide antibiotics; (ii) (2S,3S)-3-hydroxyproline 1; (iii) (2R,3S)-3-hydroxyprolinol 5, and (iv) 4'-tert-butoxyamido-2'-deoxythymidine 6b. The method features a stepwise regio- and diastereoselective reductive furylation of the protected (3S,4S)-4-methylmalimide 10, (S)-malimide 9, and a chemoselective oxidative transformation of the furyl group to the carboxyl group as the key steps. (C) 2004 Elsevier Ltd. All rights reserved.
语种	英语
出版者	PERGAMON-ELSEVIER SCIENCE LTD
内容类型	期刊论文
源URL	[http://dx.doi.org/doi:10.1016/j.tetasy.2004.10.030]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Wei-Hua Meng,Tian-Jun Wu,Hong-Kui Zhang,et al. Asymmetric syntheses of protected (2S,3S,4S)-3-hydroxy-4-methylproline and 4 '-tert-butoxyamido-2 '-deoxythymidine[J],2004.
APA	Wei-Hua Meng,Tian-Jun Wu,Hong-Kui Zhang,张洪奎,Pei-Qiang Huang,&黄培强.(2004).Asymmetric syntheses of protected (2S,3S,4S)-3-hydroxy-4-methylproline and 4 '-tert-butoxyamido-2 '-deoxythymidine..
MLA	Wei-Hua Meng,et al."Asymmetric syntheses of protected (2S,3S,4S)-3-hydroxy-4-methylproline and 4 '-tert-butoxyamido-2 '-deoxythymidine".(2004).

个性服务

查看访问统计

相关权益政策

暂无数据

收藏/分享

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。