Process modelling and simulation of a transketolase mediated reaction: Analysis of alternative modes of operation | |
Sayar, N. A.(UCL, Dept Biochem Engn, London WC1E 7JE) ; Chen, B. H. ; Chen BH(陈秉辉) ; Lye, G. J.(UCL, Dept Biochem Engn, London WC1E 7JE) ; Woodley, J. M.(Tech Univ Denmark, Dept Chem & Biochem Engn) | |
2009-03 | |
关键词 | Biocatalysis Feeding strategy Mathematical modelling Simulation Transketolase Process analysis |
英文摘要 | A previously proposed model of a transketolase catalysed carbon-carbon bond formation reaction condensing beta-hydroxypyruvate and glycolaldehyde to synthesise L-erythrulose has been extended to describe various modes of operation as an alternative to a batch process. The alternative continuous and fed-batch operations, with each substrate being fed separately and together have been analysed using the extended model. The analysis was carried out simulating the product concentration after a given time under defined process conditions. Comparison of product concentration and yield on catalyst as two process metrics were used to identify promising cases for further process development. (C) 2009 Elsevier B.V. All rights reserved. |
语种 | 英语 |
出版者 | ELSEVIER SCIENCE SA |
内容类型 | 期刊论文 |
源URL | [http://dx.doi.org/doi:10.1016/j.bej.2009.02.014] ![]() |
专题 | 化学化工-已发表论文 |
推荐引用方式 GB/T 7714 | Sayar, N. A.,Chen, B. H.,Chen BH,et al. Process modelling and simulation of a transketolase mediated reaction: Analysis of alternative modes of operation[J],2009. |
APA | Sayar, N. A.,Chen, B. H.,陈秉辉,Lye, G. J.,&Woodley, J. M..(2009).Process modelling and simulation of a transketolase mediated reaction: Analysis of alternative modes of operation.. |
MLA | Sayar, N. A.,et al."Process modelling and simulation of a transketolase mediated reaction: Analysis of alternative modes of operation".(2009). |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论