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	A new approach to 3-hydroxyprolinol derivatives by samarium diiodide-mediated reductive coupling of chiral nitrone with carbonyl compounds
	Wu, Shao-Feng ; Zheng, Xiao ; Ruan, Yuan-Ping ; Ruan YP(阮源萍) ; Huang, Pei-Qiang ; Huang PQ(黄培强)
	2009-06
英文摘要	A flexible diastereoselective approach to trans-(3S)-hydroxyprolinol derivatives is described, which is based on the samarium diiodide-mediated reductive coupling of the chiral 1-pyrroline N-oxide (nitrone)(S)-10 with carbonyl compounds. The reductive hydroxyalkylation of nitrone 10 with ketones and aromatic aldehydes is highly diastereoselective in establishing the C-2 chiral center of the pyrrolidine ring.; NSF of China [20832005]; Innovative Research Team in Science & Technology (University) in Fujian Province and the Program for New Century Excellent Talents in Xiamen University
语种	英语
出版者	ROYAL SOC CHEMISTRY
内容类型	期刊论文
源URL	[http://dx.doi.org/doi:10.1039/B906224F]
专题	化学化工－已发表论文
推荐引用方式 GB/T 7714	Wu, Shao-Feng,Zheng, Xiao,Ruan, Yuan-Ping,et al. A new approach to 3-hydroxyprolinol derivatives by samarium diiodide-mediated reductive coupling of chiral nitrone with carbonyl compounds[J],2009.
APA	Wu, Shao-Feng,Zheng, Xiao,Ruan, Yuan-Ping,阮源萍,Huang, Pei-Qiang,&黄培强.(2009).A new approach to 3-hydroxyprolinol derivatives by samarium diiodide-mediated reductive coupling of chiral nitrone with carbonyl compounds..
MLA	Wu, Shao-Feng,et al."A new approach to 3-hydroxyprolinol derivatives by samarium diiodide-mediated reductive coupling of chiral nitrone with carbonyl compounds".(2009).

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