Biochemical responses and DNA damage in red sea bream from coastal Fujian Province, China

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	Biochemical responses and DNA damage in red sea bream from coastal Fujian Province, China
	Gopalakrishnan, Singaram ; Nai, Zhang ; Thilagam, Harikrishnan ; Bei, Chen ; Ding, Jian ; Wang, Xin-Hong ; Wang, Wen-Xiong ; Ke, Cai-Huan ; Giesy, John P. ; Zhang, Xiaowei ; Wang, Ke-Jian ; Ke CH(柯才焕)
刊名	http://dx.doi.org/10.1016/j.ecoenv.2011.05.007
	2011-09
关键词	TRANSIENT OXIDATIVE STRESS GLUTATHIONE S-TRANSFERASES OXYGEN SPECIES PRODUCTION MUSSELS PERNA-VIRIDIS LIPID-PEROXIDATION GOLDFISH TISSUES ANTIOXIDANT ENZYMES RAT-BRAIN FISH LIVER
英文摘要	program for Changjiang Scholars and Innovative Research Team in University (PCSIRT) [IRT0941]; Program of Introducing Talents of Discipline to Universities [B07034]; Minjiang Scholar Program; National Science and Engineering Research Council of Canada [32; Relationships between measures of oxidative stress and adaptive antioxidant defenses were studied in red sea bream (Pagrus major, RSB) caged at eight locations along the Fujian coast, China. Oxidative damage in tissues was investigated by measuring concentrations of protein carbonyl (CP) and reactive oxygen species (ROS), lipid peroxidation (LPO), acetyl cholinesterase activity (AChE), concentration of thiol groups and activities of enzymes associated with antioxidant defense. Magnitudes of antioxidant defense parameters were significantly, positively correlated with oxidative stress. Significantly greater ROS. LPO and CP content was observed in most tissues of RSB caged at three locations relative to those at the other locations. RSB caged at one location, Meizhou, exhibited significantly more DNA damage than did RSB caged at other locations. AChE activities in liver, kidney and muscle were statistically different among locations. Multivariate analyses were used to categorize the environmental quality of different locations. The battery of measures of oxidative stress proved to be a useful integrator of oxidative stresses that could be compared among locations. (C) 2011 Elsevier Inc. All rights reserved.
语种	英语
内容类型	期刊论文
源URL	[http://dspace.xmu.edu.cn/handle/2288/60334]
专题	海洋环境－已发表论文
推荐引用方式 GB/T 7714	Gopalakrishnan, Singaram,Nai, Zhang,Thilagam, Harikrishnan,et al. Biochemical responses and DNA damage in red sea bream from coastal Fujian Province, China[J]. http://dx.doi.org/10.1016/j.ecoenv.2011.05.007,2011.
APA	Gopalakrishnan, Singaram.,Nai, Zhang.,Thilagam, Harikrishnan.,Bei, Chen.,Ding, Jian.,...&柯才焕.(2011).Biochemical responses and DNA damage in red sea bream from coastal Fujian Province, China.http://dx.doi.org/10.1016/j.ecoenv.2011.05.007.
MLA	Gopalakrishnan, Singaram,et al."Biochemical responses and DNA damage in red sea bream from coastal Fujian Province, China".http://dx.doi.org/10.1016/j.ecoenv.2011.05.007 (2011).