| Bioactive gelatin-siloxane hybrids as tissue engineering scaffold | |
| Ren, L ; Osaka, A ; Yu, B ; Shi, W ; Ge, DT ; Chen, S ; Zhang, QQ ; Sun, CJ ; Ding, J ; Gupta, M ; Chow, GM ; Kurihara, L ; Kabacoff, L ; Ren L(任磊) | |
| 2006 | |
| 关键词 | GENTAMICIN RELEASE MATRIX |
| 英文摘要 | Ca2+-containing porous gelatin-siloxane hybrids were prepared using sol-gel process, post-gelation soaking, and freeze-drying. The porosity and pore size of the hybrids could be well controlled by the freezing temperature and the pH value of the soaking solution. The pore characteristics were related to the structure change during the soaking treatment. A bone-like apatite layer was able to form in the Ca2+-containing porous gelatin-siloxane hybrids upon soaking in a stimulated body fluid. The porous gelatin-siloxane hybrids could release gentamicin sulfate which is an antibiotic drug in bone chemotherapy. Thus, those hybrid materials are proposed to find application as novel bioactive and biodegradable scaffolds in bone tissue engineering. |
| 语种 | 英语 |
| 内容类型 | 期刊论文 |
| 源URL | [http://dspace.xmu.edu.cn/handle/2288/58989]  |
| 专题 | 材料学院－已发表论文 |
| 推荐引用方式 GB/T 7714 | Ren, L,Osaka, A,Yu, B,et al. Bioactive gelatin-siloxane hybrids as tissue engineering scaffold[J],2006. |
| APA | Ren, L.,Osaka, A.,Yu, B.,Shi, W.,Ge, DT.,...&任磊.(2006).Bioactive gelatin-siloxane hybrids as tissue engineering scaffold.. |
| MLA | Ren, L,et al."Bioactive gelatin-siloxane hybrids as tissue engineering scaffold".(2006). |
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