不同巴戟天多糖对免疫活性的影响

CORC > 集美大学

	不同巴戟天多糖对免疫活性的影响
	何传波 ; 李琳 ; 汤凤霞 ; 熊何健
刊名	http://epub.edu.cnki.net/grid2008/brief/detailj.aspx?filename=zgsp201005011&dbcode=CJFQ&dbname=CJFQ2010
	2012-06-05 ; 2012-06-05
关键词	巴戟天多糖免疫活性 Morinda officinalis How polysaccharides immunological activities R285.5
其他题名	Effectes of Different Polysaccharides from Morinda Officinalis How on Immunological Activities
中文摘要	研究3种组分——巴戟天粗多糖MOP以及经离子交换和亲和柱层析得到的纯化多糖MOPI-3a和MOPA-2a对小鼠体内免疫活性的影响。以环磷酰胺诱导的免疫功能低下小鼠为试验对象,设10、30、50 mg/(kg.d)3个多糖水平处理,饲养10 d后观察不同巴戟天多糖对小鼠免疫器官指数、巨噬细胞吞噬率及外周血淋巴细胞转化率的影响。试验结果表明,各多糖低剂量组〔10 mg/(kg.d)〕对免疫的促进效果不明显,各多糖的中剂量组[30 mg/(kg.d)]免疫增强效果最为明显,达到或超过空白对照组的水平。各高剂量组[50mg/(kg.d)]与中剂量组相比,免疫促进活性无显著差异。在相同剂量下,3种多糖的免疫增强活性次序是MOPA-2a>MOPI-3a>MOP。; Effects of three different polysaccharides-MOP(crude polysaccharide),MOPI-3a(isolated by ion exchange chromatography) and MOPA-2a(isolated by affinity chromatography) from Morinda officinalis How on the immunological activities of mice were investigated in this paper.The immune suppression mice models induced by cyclophosphamide.were perfused with 10,30 and 50mg/(kg·d) polysaccharides for 10 d.The effect of polysaccharides on the immune organs index,phagocytolysis of macrophage and lymphocyte transformation rate were determined.The Results showed that,the low-dose group[10 mg/(kg·d)] of each kind of polysaccharide had almost no immunological activities.While the medium-dose group[30 mg/(kg·d)] had the strongest activities which nearly reached or exceeded those of the control group.Compared with the medium-dose group,the data of high-dose group had no significant difference.Under the same dose,the sequence of immunostimulatory effect was MOPA-2a> MOPI-3a>MOP.; 【作者单位】集美大学生物工程学院；华南理工大学轻工与食品学院；【作者英文名】He Chuanbo1 Li Lin2 Tang Fengxia1 Xiong Hejian1(1School of Bioengineering,Jimei University,Xiamen 361021,Fujian 2School of Light Chemistry and Food Science,South China University of Technology,Guangzhou 510640)
语种	中文
内容类型	期刊论文
源URL	[http://ir.calis.edu.cn/hdl/235041/18107]
专题	集美大学
推荐引用方式 GB/T 7714	何传波,李琳,汤凤霞,等. 不同巴戟天多糖对免疫活性的影响[J]. http://epub.edu.cnki.net/grid2008/brief/detailj.aspx?filename=zgsp201005011&dbcode=CJFQ&dbname=CJFQ2010,2012, 2012.
APA	何传波,李琳,汤凤霞,&熊何健.(2012).不同巴戟天多糖对免疫活性的影响.http://epub.edu.cnki.net/grid2008/brief/detailj.aspx?filename=zgsp201005011&dbcode=CJFQ&dbname=CJFQ2010.
MLA	何传波,et al."不同巴戟天多糖对免疫活性的影响".http://epub.edu.cnki.net/grid2008/brief/detailj.aspx?filename=zgsp201005011&dbcode=CJFQ&dbname=CJFQ2010 (2012).